Risk of VTE for patients with HAE in comparison with their nonaffected relatives
| Variable . | Person-years, no. . | Cases, no./persons at risk, no. . | Incidence rate, cases per 1000 person-years . | Incidence rate ratio (95% CI) . | HR (95% CI) . | |
|---|---|---|---|---|---|---|
| Model 1 . | Model 2 . | |||||
| Non-HAE | 82 911 | 68/1641 | 0.82 (0.65-1.04) | 1 (reference) | 1 (reference) | 1 (reference) |
| HAE | 18 130 | 35/365 | 1.93 (1.39-2.69) | 2.35∗∗∗ (1.57-3.54) | 2.71∗∗∗ (1.80-4.07) | 2.51∗∗∗ (1.67-3.77) |
| Variable . | Person-years, no. . | Cases, no./persons at risk, no. . | Incidence rate, cases per 1000 person-years . | Incidence rate ratio (95% CI) . | HR (95% CI) . | |
|---|---|---|---|---|---|---|
| Model 1 . | Model 2 . | |||||
| Non-HAE | 82 911 | 68/1641 | 0.82 (0.65-1.04) | 1 (reference) | 1 (reference) | 1 (reference) |
| HAE | 18 130 | 35/365 | 1.93 (1.39-2.69) | 2.35∗∗∗ (1.57-3.54) | 2.71∗∗∗ (1.80-4.07) | 2.51∗∗∗ (1.67-3.77) |
Model 1 is the univariate model. Model 2 is the multivariate model of HAE adjusted for sex, education, birth year, and country of birth. The significance levels are indicated as follows: ∗∗∗P < .001.