Table 2.

CPSS-Mol score

Score pointsGenetic risk group Bone marrow blastsWBC countRed blood cell transfusion dependency
Low <5% <13 × 109/L No 
Intermediate-1 ≥5% ≥13 × 109/L Yes 
Intermediate-2 — — — 
High — — — 
Score pointsGenetic risk group Bone marrow blastsWBC countRed blood cell transfusion dependency
Low <5% <13 × 109/L No 
Intermediate-1 ≥5% ≥13 × 109/L Yes 
Intermediate-2 — — — 
High — — — 
CPSS-Mol risk group category
Total score pointsCPSS-Mol risk groupMedian overall survival, moCumulative incidence of transformation to AML at 48 mo, %
Low Not reached 
Intermediate-1 64-68 3 (8) 
2-3 Intermediate-2 30-37 21 (24) 
≥4 High 17-18 48 (52) 
CPSS-Mol risk group category
Total score pointsCPSS-Mol risk groupMedian overall survival, moCumulative incidence of transformation to AML at 48 mo, %
Low Not reached 
Intermediate-1 64-68 3 (8) 
2-3 Intermediate-2 30-37 21 (24) 
≥4 High 17-18 48 (52) 

Adapted from Elena et al.48 

As reported in Table 1.

In the training and validation cohorts, respectively.

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