Summary of demographics and patient characteristics (full analysis set)
| Category/variable . | Part B (n = 22), n (%) . | Part D (n = 21), n (%) . |
|---|---|---|
| Age (y) | ||
| n | 22 | 21 |
| Mean (STD) | 74.0 (9.0) | 72.1 (7.8) |
| Median | 69.0 | 72.0 |
| Min, max | 62, 88 | 60, 88 |
| Sex, n (%) | ||
| Male | 16 (73) | 15 (71) |
| Female | 6 (27) | 6 (29) |
| Ethnicity, n (%) | ||
| Hispanic or Latino | 4 (18) | 1 (5) |
| Not Hispanic or Latino | 18 (82) | 20 (95) |
| Race, n (%) | ||
| Black or African American | 3 (14) | 2 (10) |
| White | 19 (86) | 19 (90) |
| Body mass index (kg/m2) | ||
| n | 22 | 21 |
| Mean (SD) | 26.7 (5.2) | 28.4 (6.2) |
| Median | 26.1 | 28.1 |
| Min, max | 18, 36 | 18, 49 |
| ECOG performance status, n (%) | ||
| Grade 0 | 6 (27) | 4 (19) |
| Grade 1 | 9 (41) | 16 (76) |
| Grade 2 | 7 (32) | 0 |
| Grade 3 | 0 | 0 |
| Missing | 0 | 1 (5) |
| Disease stage at initial diagnosis, n (%) | ||
| Stage I | 4 (18) | 3 (14) |
| Stage II | 2 (9) | 1 (5) |
| Stage III | 9 (41) | 10 (48) |
| Stage IV | 7 (32) | 6 (29) |
| Unknown | 0 | 1 (5) |
| Histologic subtype, n (%) | ||
| Nodular sclerosis | 9 (41) | 7 (33) |
| Mixed cellularity | 9 (41) | 2 (10) |
| Lymphocyte-rich | 0 | 3 (14) |
| Not otherwise specified | 3 (14) | 8 (38) |
| Other | 0 | 1 (5) |
| Category/variable . | Part B (n = 22), n (%) . | Part D (n = 21), n (%) . |
|---|---|---|
| Age (y) | ||
| n | 22 | 21 |
| Mean (STD) | 74.0 (9.0) | 72.1 (7.8) |
| Median | 69.0 | 72.0 |
| Min, max | 62, 88 | 60, 88 |
| Sex, n (%) | ||
| Male | 16 (73) | 15 (71) |
| Female | 6 (27) | 6 (29) |
| Ethnicity, n (%) | ||
| Hispanic or Latino | 4 (18) | 1 (5) |
| Not Hispanic or Latino | 18 (82) | 20 (95) |
| Race, n (%) | ||
| Black or African American | 3 (14) | 2 (10) |
| White | 19 (86) | 19 (90) |
| Body mass index (kg/m2) | ||
| n | 22 | 21 |
| Mean (SD) | 26.7 (5.2) | 28.4 (6.2) |
| Median | 26.1 | 28.1 |
| Min, max | 18, 36 | 18, 49 |
| ECOG performance status, n (%) | ||
| Grade 0 | 6 (27) | 4 (19) |
| Grade 1 | 9 (41) | 16 (76) |
| Grade 2 | 7 (32) | 0 |
| Grade 3 | 0 | 0 |
| Missing | 0 | 1 (5) |
| Disease stage at initial diagnosis, n (%) | ||
| Stage I | 4 (18) | 3 (14) |
| Stage II | 2 (9) | 1 (5) |
| Stage III | 9 (41) | 10 (48) |
| Stage IV | 7 (32) | 6 (29) |
| Unknown | 0 | 1 (5) |
| Histologic subtype, n (%) | ||
| Nodular sclerosis | 9 (41) | 7 (33) |
| Mixed cellularity | 9 (41) | 2 (10) |
| Lymphocyte-rich | 0 | 3 (14) |
| Not otherwise specified | 3 (14) | 8 (38) |
| Other | 0 | 1 (5) |
Max, maximum; Min, minimum; SD, standard deviation; y, years.