Table 4.

Scenario analyses

TreatmentCostsLife-yearsQALYsIncrementalICER per QALY
CostsQALY
5-y time horizon       
Health care sector perspective       
Liso-cel $587 874 2.91 2.29 $133 249 0.97 $136 757 
SC $454 625 1.97 1.31    
Societal perspective       
Liso-cel $702 280 2.91 2.29 $81 918 0.97 $84 075 
SC $620 361 1.97 1.31    
Alternative utilities for R/R DLBCL       
Health care sector perspective       
Liso-cel $668 624 5.34 2.70 $201 001 1.46 $137 856 
SC $467 624 2.47 1.24    
Societal perspective       
Liso-cel $882 475 5.34 2.70 $137 560 1.46 $94 346 
SC $744 914 2.47 1.24    
Long-term DLBCL survival at 5 y       
Health care sector perspective       
Liso-cel $666 431 5.34 3.64 $199 147 2.02 $98 661 
SC $467 285 2.47 1.62    
Societal perspective       
Liso-cel $880 282 5.34 3.64 $135 706 2.02 $67 232 
SC $744 575 2.47 1.62    
2023 Liso-cel list price       
Health care sector perspective       
Liso-cel $704 347 5.34 3.64 $217 651 2.02 $107 926 
SC $486 696 2.47 1.62    
Societal perspective       
Liso-cel $918 198 5.34 3.64 $154 211 2.02 $76 468 
SC $763 987 2.47 1.62    
TreatmentCostsLife-yearsQALYsIncrementalICER per QALY
CostsQALY
5-y time horizon       
Health care sector perspective       
Liso-cel $587 874 2.91 2.29 $133 249 0.97 $136 757 
SC $454 625 1.97 1.31    
Societal perspective       
Liso-cel $702 280 2.91 2.29 $81 918 0.97 $84 075 
SC $620 361 1.97 1.31    
Alternative utilities for R/R DLBCL       
Health care sector perspective       
Liso-cel $668 624 5.34 2.70 $201 001 1.46 $137 856 
SC $467 624 2.47 1.24    
Societal perspective       
Liso-cel $882 475 5.34 2.70 $137 560 1.46 $94 346 
SC $744 914 2.47 1.24    
Long-term DLBCL survival at 5 y       
Health care sector perspective       
Liso-cel $666 431 5.34 3.64 $199 147 2.02 $98 661 
SC $467 285 2.47 1.62    
Societal perspective       
Liso-cel $880 282 5.34 3.64 $135 706 2.02 $67 232 
SC $744 575 2.47 1.62    
2023 Liso-cel list price       
Health care sector perspective       
Liso-cel $704 347 5.34 3.64 $217 651 2.02 $107 926 
SC $486 696 2.47 1.62    
Societal perspective       
Liso-cel $918 198 5.34 3.64 $154 211 2.02 $76 468 
SC $763 987 2.47 1.62    

All costs were adjusted to 2022 USD; values in the table are rounded, which may result in minor discrepancies in summation.

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