Table 1. List of acquired CD38 deletions... | American Society of Hematology

Table 1.

List of acquired CD38 deletions with their respective size/location, estimated clonal level, and concurrent FC findings

Study no.	Patient age (y)	CD38 deletion			Clonal level		CD38 surface level
Study no.	Patient age (y)	Type	Chr4 location	Size	CGAT, %	FISH	CD38 surface level
1	53	Interstitial	15 740 331 to 15 859 589	119 kb	80.0	—	↓ on major subset∗
2	41	Interstitial	2 238 817 to 29 468 498	27 Mb	60.0	—	Absent on all∗
3	61	Terminal	1-39 255 744	39 Mb	20.0	ND†	↓ on major subset
4	71		1-39 466 414	39 Mb	25.0	ND†	↓ on all
5	52		1-27 752 460	28 Mb	30.0	21.5%	Absent on major subset∗
6	67		1-28 779 013	29 Mb	30.0	5.5%†	Absent on minor subset∗
7	58	Whole chromosome	Deletion 4	190 Mb	>80	6.3%†	↓ on all
8	59		Deletion 4	190 Mb	20-30	25.0%	Absent on major subset∗
9	46		Deletion 4	190 Mb	40	71%†	Absent on all∗
10	64		Deletion 4	190 Mb	10-20	18.5%	Absent on all∗

Study no.	Patient age (y)	CD38 deletion			Clonal level		CD38 surface level
Study no.	Patient age (y)	Type	Chr4 location	Size	CGAT, %	FISH	CD38 surface level
1	53	Interstitial	15 740 331 to 15 859 589	119 kb	80.0	—	↓ on major subset∗
2	41	Interstitial	2 238 817 to 29 468 498	27 Mb	60.0	—	Absent on all∗
3	61	Terminal	1-39 255 744	39 Mb	20.0	ND†	↓ on major subset
4	71		1-39 466 414	39 Mb	25.0	ND†	↓ on all
5	52		1-27 752 460	28 Mb	30.0	21.5%	Absent on major subset∗
6	67		1-28 779 013	29 Mb	30.0	5.5%†	Absent on minor subset∗
7	58	Whole chromosome	Deletion 4	190 Mb	>80	6.3%†	↓ on all
8	59		Deletion 4	190 Mb	20-30	25.0%	Absent on major subset∗
9	46		Deletion 4	190 Mb	40	71%†	Absent on all∗
10	64		Deletion 4	190 Mb	10-20	18.5%	Absent on all∗

The clonal level is reported as the proportion of CD138-enriched cells, unless otherwise specified.

Chr4, chromosome 4; ND, not detected; NR, not reported.

Received dara within 6 months.

Not CD138 enriched.