Immunosuppressive drugs used to treat AHA
| Class or drug . | 2019 guideline recommended dosing2 . | Alternative dosing (CyDRi)20 . |
|---|---|---|
| Glucocorticoids | Prednisolone or prednisone 1 mg/kg/d PO for a maximum of 4-6 weeks (followed by tapered withdrawal) | Dexamethasone 40 mg PO on days 1, 8, 15, and 22 |
| Cyclophosphamide | 1.5-2 mg/kg/d PO for a maximum of 6 weeks | 1000 mg IV on days 1 and 22 |
| Rituximab | 375 mg/m2 IV weekly for a maximum of 4 cycles | 100 mg IV on days 1, 8, 15, and 22 |
| Mycophenolate mofetil | 1 g/d for 1 week, followed by 2 g/d | — |
| Class or drug . | 2019 guideline recommended dosing2 . | Alternative dosing (CyDRi)20 . |
|---|---|---|
| Glucocorticoids | Prednisolone or prednisone 1 mg/kg/d PO for a maximum of 4-6 weeks (followed by tapered withdrawal) | Dexamethasone 40 mg PO on days 1, 8, 15, and 22 |
| Cyclophosphamide | 1.5-2 mg/kg/d PO for a maximum of 6 weeks | 1000 mg IV on days 1 and 22 |
| Rituximab | 375 mg/m2 IV weekly for a maximum of 4 cycles | 100 mg IV on days 1, 8, 15, and 22 |
| Mycophenolate mofetil | 1 g/d for 1 week, followed by 2 g/d | — |