Table 5.

Multivariable logistic regression to assess biological risk factors for underweight (weight-for-age z score less than −1) status in the combined cohort of children with SCA screened for the SPRING (low-income) and SIT (high-income) trials

VariableCombined cohorts (n = 2000)
OR95% CIP value
Age, y 1.236 1.170-1.3056 <.001 
Sex (male) 0.816 0.646-1.031 .089 
Hemoglobin (g/dL) 0.588 0.506-0.684 <.001 
White blood cell count (× 109/L) 0.979 0.953-1.007 .134 
Group (SPRING)  1.947 0.314-12.067 .474 
Interaction of hemoglobin by group  1.379 1.03-1.740 .007 
VariableCombined cohorts (n = 2000)
OR95% CIP value
Age, y 1.236 1.170-1.3056 <.001 
Sex (male) 0.816 0.646-1.031 .089 
Hemoglobin (g/dL) 0.588 0.506-0.684 <.001 
White blood cell count (× 109/L) 0.979 0.953-1.007 .134 
Group (SPRING)  1.947 0.314-12.067 .474 
Interaction of hemoglobin by group  1.379 1.03-1.740 .007 

Abbreviations are explained in Table 1.

Reference category is SIT.

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