Nutritional status in children with SCA screened for the SPRING (low-income) and SIT (high-income) trials
| Nutritional status, n (%) . | SPRING (n = 928) . | SIT (n = 1093) . | P value∗ . | Combined (N = 2021) . |
|---|---|---|---|---|
| Underweight | ||||
| No deficit, weight-for-age z score ≥ −1 (SD) | 112 (12.1) | 812 (74.3) | <.001 | 924 (45.7) |
| Overall underweight, weight-for-age z score < −1 (SD) | 816 (87.9) | 281 (25.7) | 1097 (54.3) | |
| Mild underweight, weight-for-age z score < −1 and ≥ −2 (SD) | 279 (30.1) | 227 (20.8) | 506 (25.0) | |
| Moderate, weight-for-age z score < −2 and ≥ −3 (SD) | 326 (35.1) | 46 (4.2) | 372 (18.4) | |
| Severe underweight, weight-for-age z score < −3 (SD) | 211 (22.7) | 8 (0.7) | 219 (10.8) | |
| Stunted | <.001 | |||
| No deficit, height-for-age z score ≥ −1 (SD) | 281 (30.3) | 731 (66.9) | 1012 (50.1) | |
| Overall stunted, height-for-age z score < −1 (SD) | 647 (69.7) | 362 (33.1) | 1009 (49.9) | |
| Mild, height-for-age z score < −1 and ≥ −2 (SD) | 301 (32.4) | 265 (24.2) | 566 (28.0) | |
| Moderate, height-for-age z score < −2 and ≥ −3 (SD) | 222 (24.2) | 82 (7.5) | 304 (15.0) | |
| Severe, height-for-age z score < −3 (SD) | 124 (13.8) | 15 (1.4) | 139 (6.9) | |
| Wasted | <.001 | |||
| No deficit, BMI z score ≥ −1 (SD) | 232 (25.0) | 895 (81.9) | 1127 (55.8) | |
| Overall wasted, BMI z score < −1 (SD) | 696 (75.0) | 198 (18.1) | 894 (44.2) | |
| Mild, BMI z score < −1 and ≥ −2 (SD) | 274 (29.5) | 162 (14.8) | 436 (21.6) | |
| Moderate, BMI z score < −2 and ≥ −3 (SD) | 228 (24.6) | 32 (2.9) | 260 (12.9) | |
| Severe, BMI z score < −3 (SD) | 194 (20.9) | 4 (0.4) | 198 (9.8) |
| Nutritional status, n (%) . | SPRING (n = 928) . | SIT (n = 1093) . | P value∗ . | Combined (N = 2021) . |
|---|---|---|---|---|
| Underweight | ||||
| No deficit, weight-for-age z score ≥ −1 (SD) | 112 (12.1) | 812 (74.3) | <.001 | 924 (45.7) |
| Overall underweight, weight-for-age z score < −1 (SD) | 816 (87.9) | 281 (25.7) | 1097 (54.3) | |
| Mild underweight, weight-for-age z score < −1 and ≥ −2 (SD) | 279 (30.1) | 227 (20.8) | 506 (25.0) | |
| Moderate, weight-for-age z score < −2 and ≥ −3 (SD) | 326 (35.1) | 46 (4.2) | 372 (18.4) | |
| Severe underweight, weight-for-age z score < −3 (SD) | 211 (22.7) | 8 (0.7) | 219 (10.8) | |
| Stunted | <.001 | |||
| No deficit, height-for-age z score ≥ −1 (SD) | 281 (30.3) | 731 (66.9) | 1012 (50.1) | |
| Overall stunted, height-for-age z score < −1 (SD) | 647 (69.7) | 362 (33.1) | 1009 (49.9) | |
| Mild, height-for-age z score < −1 and ≥ −2 (SD) | 301 (32.4) | 265 (24.2) | 566 (28.0) | |
| Moderate, height-for-age z score < −2 and ≥ −3 (SD) | 222 (24.2) | 82 (7.5) | 304 (15.0) | |
| Severe, height-for-age z score < −3 (SD) | 124 (13.8) | 15 (1.4) | 139 (6.9) | |
| Wasted | <.001 | |||
| No deficit, BMI z score ≥ −1 (SD) | 232 (25.0) | 895 (81.9) | 1127 (55.8) | |
| Overall wasted, BMI z score < −1 (SD) | 696 (75.0) | 198 (18.1) | 894 (44.2) | |
| Mild, BMI z score < −1 and ≥ −2 (SD) | 274 (29.5) | 162 (14.8) | 436 (21.6) | |
| Moderate, BMI z score < −2 and ≥ −3 (SD) | 228 (24.6) | 32 (2.9) | 260 (12.9) | |
| Severe, BMI z score < −3 (SD) | 194 (20.9) | 4 (0.4) | 198 (9.8) |
SD, standard deviation.
χ2 test, comparison of no deficit with the overall category for each condition.