Table 2.

Nutritional status in children with SCA screened for the SPRING (low-income) and SIT (high-income) trials

Nutritional status, n (%)SPRING (n = 928)SIT (n = 1093)P value Combined (N = 2021)
Underweight     
No deficit, weight-for-age z score ≥ −1 (SD) 112 (12.1) 812 (74.3) <.001 924 (45.7) 
Overall underweight, weight-for-age z score < −1 (SD) 816 (87.9) 281 (25.7)  1097 (54.3) 
Mild underweight, weight-for-age z score < −1 and ≥ −2 (SD) 279 (30.1) 227 (20.8)  506 (25.0) 
Moderate, weight-for-age z score < −2 and ≥ −3 (SD) 326 (35.1) 46 (4.2)  372 (18.4) 
Severe underweight, weight-for-age z score < −3 (SD) 211 (22.7) 8 (0.7)  219 (10.8) 
Stunted   <.001  
No deficit, height-for-age z score ≥ −1 (SD) 281 (30.3) 731 (66.9)  1012 (50.1) 
Overall stunted, height-for-age z score < −1 (SD) 647 (69.7) 362 (33.1)  1009 (49.9) 
Mild, height-for-age z score < −1 and ≥ −2 (SD) 301 (32.4) 265 (24.2)  566 (28.0) 
Moderate, height-for-age z score < −2 and ≥ −3 (SD) 222 (24.2) 82 (7.5)  304 (15.0) 
Severe, height-for-age z score < −3 (SD) 124 (13.8) 15 (1.4)  139 (6.9) 
Wasted   <.001  
No deficit, BMI z score ≥ −1 (SD) 232 (25.0) 895 (81.9)  1127 (55.8) 
Overall wasted, BMI z score < −1 (SD) 696 (75.0) 198 (18.1)  894 (44.2) 
Mild, BMI z score < −1 and ≥ −2 (SD) 274 (29.5) 162 (14.8)  436 (21.6) 
Moderate, BMI z score < −2 and ≥ −3 (SD) 228 (24.6) 32 (2.9)  260 (12.9) 
Severe, BMI z score < −3 (SD) 194 (20.9) 4 (0.4)  198 (9.8) 
Nutritional status, n (%)SPRING (n = 928)SIT (n = 1093)P value Combined (N = 2021)
Underweight     
No deficit, weight-for-age z score ≥ −1 (SD) 112 (12.1) 812 (74.3) <.001 924 (45.7) 
Overall underweight, weight-for-age z score < −1 (SD) 816 (87.9) 281 (25.7)  1097 (54.3) 
Mild underweight, weight-for-age z score < −1 and ≥ −2 (SD) 279 (30.1) 227 (20.8)  506 (25.0) 
Moderate, weight-for-age z score < −2 and ≥ −3 (SD) 326 (35.1) 46 (4.2)  372 (18.4) 
Severe underweight, weight-for-age z score < −3 (SD) 211 (22.7) 8 (0.7)  219 (10.8) 
Stunted   <.001  
No deficit, height-for-age z score ≥ −1 (SD) 281 (30.3) 731 (66.9)  1012 (50.1) 
Overall stunted, height-for-age z score < −1 (SD) 647 (69.7) 362 (33.1)  1009 (49.9) 
Mild, height-for-age z score < −1 and ≥ −2 (SD) 301 (32.4) 265 (24.2)  566 (28.0) 
Moderate, height-for-age z score < −2 and ≥ −3 (SD) 222 (24.2) 82 (7.5)  304 (15.0) 
Severe, height-for-age z score < −3 (SD) 124 (13.8) 15 (1.4)  139 (6.9) 
Wasted   <.001  
No deficit, BMI z score ≥ −1 (SD) 232 (25.0) 895 (81.9)  1127 (55.8) 
Overall wasted, BMI z score < −1 (SD) 696 (75.0) 198 (18.1)  894 (44.2) 
Mild, BMI z score < −1 and ≥ −2 (SD) 274 (29.5) 162 (14.8)  436 (21.6) 
Moderate, BMI z score < −2 and ≥ −3 (SD) 228 (24.6) 32 (2.9)  260 (12.9) 
Severe, BMI z score < −3 (SD) 194 (20.9) 4 (0.4)  198 (9.8) 

SD, standard deviation.

χ2 test, comparison of no deficit with the overall category for each condition.

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