Table 1.

Characteristics of the children with SCA screened for the SPRING (low-income) and SIT (high-income) trials

VariableSPRING cohort (n = 928)SIT cohort (n = 1093)P value 
Age (y), median (IQR) 8.1 (6.3-10.3) 8.5 (6.8-10.6) <.001 
Sex (male), n (%) 455 (49.0) 555 (50.8) .434 
Hemoglobin (g/dL), mean (SD) 7.5 (1.1) (n = 913) 8.1 (1.1) (n = 1092) <.001 
White blood cell count (×109/L), mean (SD) 14.7 (5.1) (n = 913) 12.4 (3.9) (n = 1088) <.001 
Weight (kg), mean (SD) 19.5 (4.4) 27.3 (7.9) <.001 
Height (cm), mean (SD) 119.3 (11.6) 127.9 (12.7) <.001 
BMI (kg/m2), mean (SD) 13.6 (1.7) 16.3 (2.3) <.001 
Weight-for-age z score, mean (SD) −2.21 (1.1) −0.33 (1.1) <.001 
Height-for-age z score, mean (SD) −1.59 (1.3) −0.53 (1.1) <.001 
BMI z score, mean (SD) −1.93 (1.4) −0.06 (1.1) <.001 
VariableSPRING cohort (n = 928)SIT cohort (n = 1093)P value 
Age (y), median (IQR) 8.1 (6.3-10.3) 8.5 (6.8-10.6) <.001 
Sex (male), n (%) 455 (49.0) 555 (50.8) .434 
Hemoglobin (g/dL), mean (SD) 7.5 (1.1) (n = 913) 8.1 (1.1) (n = 1092) <.001 
White blood cell count (×109/L), mean (SD) 14.7 (5.1) (n = 913) 12.4 (3.9) (n = 1088) <.001 
Weight (kg), mean (SD) 19.5 (4.4) 27.3 (7.9) <.001 
Height (cm), mean (SD) 119.3 (11.6) 127.9 (12.7) <.001 
BMI (kg/m2), mean (SD) 13.6 (1.7) 16.3 (2.3) <.001 
Weight-for-age z score, mean (SD) −2.21 (1.1) −0.33 (1.1) <.001 
Height-for-age z score, mean (SD) −1.59 (1.3) −0.53 (1.1) <.001 
BMI z score, mean (SD) −1.93 (1.4) −0.06 (1.1) <.001 

IQR, interquartile range; SD, standard deviation.

χ2 test for percentages, t test for means, and Mann-Whitney U test for medians.

or Create an Account

Close Modal
Close Modal