Characteristics of monoclonal anti-FVIII antibodies (Ab1-7)
| Antibody . | Epitope . | Source . | Isotype . | Reactivity . | FVIII inhibition . |
|---|---|---|---|---|---|
| 1 | C1 | Mouse | IgG2a | Human | + |
| 2 | A2 | Mouse | IgG2a | Human | + |
| 3 | A1A3 | Mouse | IgG2a | Human | + |
| 4 | C2 (2303-2332) | Mouse | IgG2a | Human, rabbit, baboon | + |
| 5 | C2 (2248-2285) | Mouse | IgG2a | Human, baboon | + |
| 6 | A1 | Mouse | IgG2a | Human, canine | - |
| 7 | A3 | Mouse | IgG1 | Human | + |
| Antibody . | Epitope . | Source . | Isotype . | Reactivity . | FVIII inhibition . |
|---|---|---|---|---|---|
| 1 | C1 | Mouse | IgG2a | Human | + |
| 2 | A2 | Mouse | IgG2a | Human | + |
| 3 | A1A3 | Mouse | IgG2a | Human | + |
| 4 | C2 (2303-2332) | Mouse | IgG2a | Human, rabbit, baboon | + |
| 5 | C2 (2248-2285) | Mouse | IgG2a | Human, baboon | + |
| 6 | A1 | Mouse | IgG2a | Human, canine | - |
| 7 | A3 | Mouse | IgG1 | Human | + |