Table 2.

Response by regimen category

Patients ever achieved a response Patients with evaluable regimen, n
Yes, n (%)No, n (%)
Anti-IL6 w/wo corticosteroids  29 (50.0) 29 (50.0) 58 
Siltuximab w/wo corticosteroids 22 (52.4) 20 (47.6) 42 
Tocilizumab w/wo corticosteroids 8 (44.4) 10 (55.6) 18 
Rituximab w/wo corticosteroids 7 (26.9) 19 (73.1) 26 
Chemotherapy-based regimen 13 (52.0) 12 (48.0) 25 
Immunomodulator w/wo corticosteroids 4 (19.0) 17 (81.0) 21 
Anti-IL6 + rituximab w/wo other 5 (41.7) 7 (58.3) 12 
Anti-IL6 + immunomodulator(s) w/wo corticosteroids 6 (60.0) 4 (40.0) 10 
Anti-IL6 + procedure w/wo corticosteroids 1 (100) 
Rituximab + immunomodulator(s) w/wo corticosteroids 1 (12.5) 7 (87.5) 
Corticosteroids 1 (2.8) 35 (97.2) 36 
Procedure + drug therapy 1 (25.0) 3 (75.0) 
Procedure 2 (100) 
No medical treatment 2 (100) 
Patients ever achieved a response Patients with evaluable regimen, n
Yes, n (%)No, n (%)
Anti-IL6 w/wo corticosteroids  29 (50.0) 29 (50.0) 58 
Siltuximab w/wo corticosteroids 22 (52.4) 20 (47.6) 42 
Tocilizumab w/wo corticosteroids 8 (44.4) 10 (55.6) 18 
Rituximab w/wo corticosteroids 7 (26.9) 19 (73.1) 26 
Chemotherapy-based regimen 13 (52.0) 12 (48.0) 25 
Immunomodulator w/wo corticosteroids 4 (19.0) 17 (81.0) 21 
Anti-IL6 + rituximab w/wo other 5 (41.7) 7 (58.3) 12 
Anti-IL6 + immunomodulator(s) w/wo corticosteroids 6 (60.0) 4 (40.0) 10 
Anti-IL6 + procedure w/wo corticosteroids 1 (100) 
Rituximab + immunomodulator(s) w/wo corticosteroids 1 (12.5) 7 (87.5) 
Corticosteroids 1 (2.8) 35 (97.2) 36 
Procedure + drug therapy 1 (25.0) 3 (75.0) 
Procedure 2 (100) 
No medical treatment 2 (100) 

Patients with >1 instance of the same regimen category are considered to have achieved response if response was achieved at least 1 time.

Includes patients ever treated with either siltuximab w/wo corticosteroids and/or tocilizumab w/wo corticosteroids. Best response among those regimens is included; therefore, the number of patients who are evaluable for each siltuximab w/wo corticosteroids and tocilizumab w/wo corticosteroids may not sum to the number of patients who are evaluable for anti-IL6 w/wo corticosteroids

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