Risk factors for developing GVHD after orthotopic liver and intestinal transplantation
Orthotopic liver4,10,25-30 . | Intestinal and MV5,31,32 . |
---|---|
Donor-recipient HLA matching | Multivisceral or liver-included graft |
Recipient age >40 y | Larger graft volume |
Donor-recipient age difference >20 y | Transplant for MIAI |
Recipient glucose intolerance | Retransplantation |
Recipient infection with CMV or HSV | |
Transplant for AALD, HCC, or AILD | |
Liver allograft with ≥6% steatosis | |
Donor death from CVA | |
Donor-recipient race mismatching | |
Use of induction immunosuppression |
Orthotopic liver4,10,25-30 . | Intestinal and MV5,31,32 . |
---|---|
Donor-recipient HLA matching | Multivisceral or liver-included graft |
Recipient age >40 y | Larger graft volume |
Donor-recipient age difference >20 y | Transplant for MIAI |
Recipient glucose intolerance | Retransplantation |
Recipient infection with CMV or HSV | |
Transplant for AALD, HCC, or AILD | |
Liver allograft with ≥6% steatosis | |
Donor death from CVA | |
Donor-recipient race mismatching | |
Use of induction immunosuppression |
AALD, alcohol-associated liver disease; AILD, autoimmune liver disease; CVA, cerebrovascular accident; HCC, hepatocellular carcinoma; MIAI, multiple intestinal atresia and immunodeficiency; MV, multivisceral transplantation.