Factors associated with the composite outcome of 7-day mortality or ICU admission
| Factor . | Composite outcome, N (%) . | Univariate analysis . | Multivariable analysis . | |||||
|---|---|---|---|---|---|---|---|---|
| Y (n = 22) . | N (n = 36) . | P-value . | OR . | 95% CI . | P-value . | OR . | 95% CI . | |
| exoU+ genotype | 11 (50) | 7 (19.4) | .02 | 4.1 | 1.3-13.4 | .02 | 5.2 | 1.4-19.7 |
| Neutropenia | 17 (77.2) | 27 (75) | .72 | |||||
| Profound neutropenia | 15 (68.2) | 23 (63.9) | .91 | |||||
| Pneumonia | 12 (54.5) | 6 (16.7) | .004 | 6 | 1.7-20.2 | .003 | 7.3 | 1.9-27.6 |
| MDR isolate | 2 (9.1) | 6 (16.7) | .66 | |||||
| Steroid receipt | 8 (36.4) | 13 (36.1) | .66 | |||||
| IEAT | 2 (9.1) | 5 (13.9) | .88 | |||||
| Male sex | 14 (63.6) | 25 (69.4) | .82 | |||||
| HCT recipient | 10 (45.5) | 15 (41.7) | .53 | |||||
| Copathogen | 5 (22.7) | 9 (25) | .71 | |||||
| Age, y (median) | 64 | 61 | .73 | |||||
| Factor . | Composite outcome, N (%) . | Univariate analysis . | Multivariable analysis . | |||||
|---|---|---|---|---|---|---|---|---|
| Y (n = 22) . | N (n = 36) . | P-value . | OR . | 95% CI . | P-value . | OR . | 95% CI . | |
| exoU+ genotype | 11 (50) | 7 (19.4) | .02 | 4.1 | 1.3-13.4 | .02 | 5.2 | 1.4-19.7 |
| Neutropenia | 17 (77.2) | 27 (75) | .72 | |||||
| Profound neutropenia | 15 (68.2) | 23 (63.9) | .91 | |||||
| Pneumonia | 12 (54.5) | 6 (16.7) | .004 | 6 | 1.7-20.2 | .003 | 7.3 | 1.9-27.6 |
| MDR isolate | 2 (9.1) | 6 (16.7) | .66 | |||||
| Steroid receipt | 8 (36.4) | 13 (36.1) | .66 | |||||
| IEAT | 2 (9.1) | 5 (13.9) | .88 | |||||
| Male sex | 14 (63.6) | 25 (69.4) | .82 | |||||
| HCT recipient | 10 (45.5) | 15 (41.7) | .53 | |||||
| Copathogen | 5 (22.7) | 9 (25) | .71 | |||||
| Age, y (median) | 64 | 61 | .73 | |||||
CI, confidence interval; IEAT, inappropriate empiric antibiotic therapy; MDR, multidrug resistant; OR, odds ratio.