Comparison of PRO scores between adults with SCD who likely have chronic pain and those who likely do not have chronic pain
| PRO domains . | Chronic pain (n = 14) Median (IQR) . | No chronic pain (n = 19) Median (IQR) . | P value∗ . |
|---|---|---|---|
| Pain-related | |||
| PROMIS pain interference | 64.2 (60.5-68.7) | 54.3 (45.7-59) | .001 |
| PROMIS pain behavior | 63.2 (61.9-65) | 50 (35.3-60.1) | .004 |
| ASCQ-Me pain impact | 42.9 (37.3-48.4) | 53.2 (42.5-65.8) | .013 |
| Pain quality | |||
| PROMIS nociceptive | 47.5 (44.4-50.5) | 37 (30-64.9) | .305 |
| PROMIS neuropathic | 51.8 (50.4-54.4) | 37 (37-50.4) | .006 |
| painDETECT | 15 (11.8-22.8) | 9 (6-12) | .011 |
| Nonpain-related | |||
| PROMIS fatigue | 60.7 (56.5-69.7) | 52.8 (45.2-60.4) | .032 |
| PROMIS sleep disturbance | 63 (57-65.8) | 56.5 (44.2-60.2) | .014 |
| PROMIS depression | 54.9 (51.2-62.2) | 48.2 (34.2-57.5) | .026 |
| PROMIS anxiety | 59.7 (52.4-70.8) | 53.1 (38.4-65.6) | .078 |
| ASCQ-Me emotional impact | 45.3 (39.2-51.7) | 60.3 (44.5-67.4) | .019 |
| PRO domains . | Chronic pain (n = 14) Median (IQR) . | No chronic pain (n = 19) Median (IQR) . | P value∗ . |
|---|---|---|---|
| Pain-related | |||
| PROMIS pain interference | 64.2 (60.5-68.7) | 54.3 (45.7-59) | .001 |
| PROMIS pain behavior | 63.2 (61.9-65) | 50 (35.3-60.1) | .004 |
| ASCQ-Me pain impact | 42.9 (37.3-48.4) | 53.2 (42.5-65.8) | .013 |
| Pain quality | |||
| PROMIS nociceptive | 47.5 (44.4-50.5) | 37 (30-64.9) | .305 |
| PROMIS neuropathic | 51.8 (50.4-54.4) | 37 (37-50.4) | .006 |
| painDETECT | 15 (11.8-22.8) | 9 (6-12) | .011 |
| Nonpain-related | |||
| PROMIS fatigue | 60.7 (56.5-69.7) | 52.8 (45.2-60.4) | .032 |
| PROMIS sleep disturbance | 63 (57-65.8) | 56.5 (44.2-60.2) | .014 |
| PROMIS depression | 54.9 (51.2-62.2) | 48.2 (34.2-57.5) | .026 |
| PROMIS anxiety | 59.7 (52.4-70.8) | 53.1 (38.4-65.6) | .078 |
| ASCQ-Me emotional impact | 45.3 (39.2-51.7) | 60.3 (44.5-67.4) | .019 |
Significant P values are shown in bold.
FDR, false discovery rate.
FDR adjusted P values based on Mann-Whitney U test.