Demographic and clinical characteristics of the study cohort (n = 2465)
| General characteristics . | . |
|---|---|
| Age, mean (SD) | 69.2 (9.1) |
| Smoking, n (%) | 241 (9.8%) |
| Comorbidities, n (%) | |
| Eczema, n (%) | 64 (2.6%) |
| Coronary artery disease, n (%) | 218 (8.8%) |
| Hypertension, n (%) | 634 (26.0%) |
| Diabetes, n (%) | 110 (4.5%) |
| Thyroid disease, n (%) | 517 (21%) |
| Dyslipidemia, n (%) | 445 (18.0%) |
| Venous thrombosis, n (%) | 123 (5.0%) |
| Asthma, n (%) | 183 (7.4%) |
| Lupus, n (%) | 9 (0.4%) |
| Previous cancer, n (%) | 259 (11.0%) |
| CH status | |
| CHIP, n (%) | 333 (14.0%) |
| TET2 mutation, n (%) | 103 (4.2%) |
| DNMT3A mutation, n (%) | 195 (7.9%) |
| Peripheral blood counts | |
| Total white blood count, 109/L, mean (SD) | 6.43 (1.63) |
| Absolute lymphocyte count, 109/L, mean (SD) | 1.86 (0.57) |
| Absolute neutrophil count, 109/L, mean (SD) | 3.93 (1.29) |
| Absolute monocyte count, 109/L, mean (SD) | 0.46 (0.16) |
| Hemoglobin, g/L, mean (SD) | 131.2 (9.67) |
| Mean corpuscular volume, fL, mean (SD) | 91.1 (3.9) |
| Platelet count, 109/L, mean (SD) | 249.2 (57.6) |
| General characteristics . | . |
|---|---|
| Age, mean (SD) | 69.2 (9.1) |
| Smoking, n (%) | 241 (9.8%) |
| Comorbidities, n (%) | |
| Eczema, n (%) | 64 (2.6%) |
| Coronary artery disease, n (%) | 218 (8.8%) |
| Hypertension, n (%) | 634 (26.0%) |
| Diabetes, n (%) | 110 (4.5%) |
| Thyroid disease, n (%) | 517 (21%) |
| Dyslipidemia, n (%) | 445 (18.0%) |
| Venous thrombosis, n (%) | 123 (5.0%) |
| Asthma, n (%) | 183 (7.4%) |
| Lupus, n (%) | 9 (0.4%) |
| Previous cancer, n (%) | 259 (11.0%) |
| CH status | |
| CHIP, n (%) | 333 (14.0%) |
| TET2 mutation, n (%) | 103 (4.2%) |
| DNMT3A mutation, n (%) | 195 (7.9%) |
| Peripheral blood counts | |
| Total white blood count, 109/L, mean (SD) | 6.43 (1.63) |
| Absolute lymphocyte count, 109/L, mean (SD) | 1.86 (0.57) |
| Absolute neutrophil count, 109/L, mean (SD) | 3.93 (1.29) |
| Absolute monocyte count, 109/L, mean (SD) | 0.46 (0.16) |
| Hemoglobin, g/L, mean (SD) | 131.2 (9.67) |
| Mean corpuscular volume, fL, mean (SD) | 91.1 (3.9) |
| Platelet count, 109/L, mean (SD) | 249.2 (57.6) |
Entries correspond to frequency (%) for categorical data and mean (SD) for continuous data.
SD, standard deviation.