Summary of the comparisons of WB- and PPP-TG between intrinsic factors–deficient mice and wild-type mice
| . | Silica . | 0.05 pM TF . | 0.5 pM TF . | |||
|---|---|---|---|---|---|---|
| WB-TG . | PPP-TG . | WB-TG . | PPP-TG . | WB-TG . | PPP-TG . | |
| F12−/− vs F12+/+ | ||||||
| Lag time | ≈ | + + | ≈ | ≈ | ND | ND |
| Peak height & ETP | − | − − | ≈ | ≈ | ND | ND |
| F11−/− vs F11+/+ | ||||||
| Lag time | + | + + | ≈ | ≈ | ≈ | ≈ |
| Peak height & ETP | − | − − | − | ≈ | ≈ | ≈ |
| F9−/− vs F9+/+ | ||||||
| Lag time | + + | + + | + + | + | + | ≈ |
| Peak height & ETP | − − | − − | − − | − | − | ≈ |
| . | Silica . | 0.05 pM TF . | 0.5 pM TF . | |||
|---|---|---|---|---|---|---|
| WB-TG . | PPP-TG . | WB-TG . | PPP-TG . | WB-TG . | PPP-TG . | |
| F12−/− vs F12+/+ | ||||||
| Lag time | ≈ | + + | ≈ | ≈ | ND | ND |
| Peak height & ETP | − | − − | ≈ | ≈ | ND | ND |
| F11−/− vs F11+/+ | ||||||
| Lag time | + | + + | ≈ | ≈ | ≈ | ≈ |
| Peak height & ETP | − | − − | − | ≈ | ≈ | ≈ |
| F9−/− vs F9+/+ | ||||||
| Lag time | + + | + + | + + | + | + | ≈ |
| Peak height & ETP | − − | − − | − − | − | − | ≈ |
Mouse WB was collected in citrate and 50 μg/mL CTI. TGs in WB and PPP were triggered by 9 mM CaCl2 and either 0.05/0.5 pM TF or 120× diluted silica (4 μM phospholipids were added in PPP).
≈, nonsignificantly different; − or +, modestly reduced or prolonged; − − or + +, severely reduced or prolonged; ND, not determined.