Discordant clones in the PB vs BM
| Patient . | Variant . | VAF in PB (%) . | VAF in BM (%) . | VAF in PB 6-12 mo (%) . | VAF in PB 12-17 mo (%) . |
|---|---|---|---|---|---|
| 31 | CHEK2 Ile459AsnfsTer7 | 3.04 | 1.15 | 3.79 | 3.62 |
| 31 | DNMT3A Phe731Ile | Undetectable | 0.07 | Undetectable | Undetectable |
| 31 | DNMT3A Cys517Ter | 3.11 | 1.78 | 2.29 | 3.95 |
| 31 | TET2 His1717IlefsTer3 | 0.88 | 0.51 | 0.19 | 0.12 |
| 31 | TP53 Arg282Trp | 1.97 | 0.62 | 0.75 | 1.49 |
| 35 | ASXL1 Cys193Arg | 0.13 | 1.38 | Undetectable | No sample |
| 35 | ASXL1 Ser207Gly | 0.10 | 1.05 | Undetectable | No sample |
| 35 | DNMT3A splice site | 5.78 | 0.87 | 3.99 | No sample |
| 42 | ATM Thr306Arg | 1.54 | Undetectable | No sample | No sample |
| 43 | APC Ser1126Arg | Undetectable | 1.16 | No sample | No sample |
| 43 | CARD11 Thr532Met | Undetectable | 5.51 | No sample | No sample |
| 43 | NOTCH1 Arg1263His | Undetectable | 6.38 | No sample | No sample |
| 43 | SPEN Arg2305_Ala2306delinsSer | Undetectable | 5.99 | No sample | No sample |
| 43 | TET2 Gly1606Ala | Undetectable | 5.30 | No sample | No sample |
| Patient . | Variant . | VAF in PB (%) . | VAF in BM (%) . | VAF in PB 6-12 mo (%) . | VAF in PB 12-17 mo (%) . |
|---|---|---|---|---|---|
| 31 | CHEK2 Ile459AsnfsTer7 | 3.04 | 1.15 | 3.79 | 3.62 |
| 31 | DNMT3A Phe731Ile | Undetectable | 0.07 | Undetectable | Undetectable |
| 31 | DNMT3A Cys517Ter | 3.11 | 1.78 | 2.29 | 3.95 |
| 31 | TET2 His1717IlefsTer3 | 0.88 | 0.51 | 0.19 | 0.12 |
| 31 | TP53 Arg282Trp | 1.97 | 0.62 | 0.75 | 1.49 |
| 35 | ASXL1 Cys193Arg | 0.13 | 1.38 | Undetectable | No sample |
| 35 | ASXL1 Ser207Gly | 0.10 | 1.05 | Undetectable | No sample |
| 35 | DNMT3A splice site | 5.78 | 0.87 | 3.99 | No sample |
| 42 | ATM Thr306Arg | 1.54 | Undetectable | No sample | No sample |
| 43 | APC Ser1126Arg | Undetectable | 1.16 | No sample | No sample |
| 43 | CARD11 Thr532Met | Undetectable | 5.51 | No sample | No sample |
| 43 | NOTCH1 Arg1263His | Undetectable | 6.38 | No sample | No sample |
| 43 | SPEN Arg2305_Ala2306delinsSer | Undetectable | 5.99 | No sample | No sample |
| 43 | TET2 Gly1606Ala | Undetectable | 5.30 | No sample | No sample |