Table 2.

Multivariate Cox regression analysis of risk factors for time to reactivation at more than or equal to 250 and 1000 IU/mL before day 100 posttransplant

≥250 IU/mL
CovariateCategoryHR (95% CI)P
GVHD prevention method MTX  
 MMF 1.50 (0.97-2.32) .067 
 PTCy 1.64 (1.03-2.61) .039 
Donor relationship Sibling  
 Unrelated 1.44 (0.99-2.08) .054 
Donor CMV serostatus −  
 0.94 (0.74-1.21) .643 
Conditioning regimen Nonmyeloablative/RIC  
 Myeloablative 1.23 (0.80-1.89) .349 
Recipient age at transplant As continuous 1.00 (0.99-1.01) .576 
Donor age at transplant As continuous 0.99 (0.98-1.00) .063 
≥250 IU/mL
CovariateCategoryHR (95% CI)P
GVHD prevention method MTX  
 MMF 1.50 (0.97-2.32) .067 
 PTCy 1.64 (1.03-2.61) .039 
Donor relationship Sibling  
 Unrelated 1.44 (0.99-2.08) .054 
Donor CMV serostatus −  
 0.94 (0.74-1.21) .643 
Conditioning regimen Nonmyeloablative/RIC  
 Myeloablative 1.23 (0.80-1.89) .349 
Recipient age at transplant As continuous 1.00 (0.99-1.01) .576 
Donor age at transplant As continuous 0.99 (0.98-1.00) .063 
≥1000 IU/mL
CovariateCategoryHR (95% CI)P
GVHD prevention method MTX  
 MMF 1.36 (0.68-2.72) .391 
 PTCy 1.22 (0.49-3.03) .663 
Donor relationship Sibling  
 Unrelated 1.61 (0.84-3.09) .15 
Donor CMV serostatus −  
 0.83 (0.55-1.26) .379 
Conditioning regimen Nonmyeloablative/RIC  
 Myeloablative 0.76 (0.39-1.48) .423 
Recipient age at transplant As continuous 1.00 (0.98-1.02) .974 
Donor age at transplant As continuous 0.99 (0.97-1.01) .392 
≥1000 IU/mL
CovariateCategoryHR (95% CI)P
GVHD prevention method MTX  
 MMF 1.36 (0.68-2.72) .391 
 PTCy 1.22 (0.49-3.03) .663 
Donor relationship Sibling  
 Unrelated 1.61 (0.84-3.09) .15 
Donor CMV serostatus −  
 0.83 (0.55-1.26) .379 
Conditioning regimen Nonmyeloablative/RIC  
 Myeloablative 0.76 (0.39-1.48) .423 
Recipient age at transplant As continuous 1.00 (0.98-1.02) .974 
Donor age at transplant As continuous 0.99 (0.97-1.01) .392 

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