Table 1. Patient information Sample ID .... | American Society of Hematology

Table 1.

Patient information

Sample ID	Age	Sex	ISCL stage	B stage	CTCL subtype	Clinically abnormal phenotype	% CD4⁺CD26⁻	Abs. abn.∗ (/μL)	Treatment
P1	81	M	IVA	B2	SS	CD3dim⁺ CD4⁺ CD7⁻ CD26⁻ CD2⁺ CD8⁻ CD10⁻ CD5⁺	87.8	1818.3	ECP, ACIT
P2	76	M	IIB	B1	MF	CD3dim⁺ CD4⁺ CD7⁻ CD26⁻ CD8⁻ CD5⁺ CD2⁺	37.4	1774.6	ECP, BEX
P3	72	F	IVA	B2	SS	CD3⁺ CD4⁺ CD7Var⁺ CD26⁻ CD8⁻ CD2⁺ CD25⁻	82.6	2799.6	ECP, BEX, IFN-α
P4	79	M	IA	B1	MF	CD3dim⁺ CD4⁺ CD7⁻ CD26⁻ CD2⁺	61.2	964.5	ECP, BEX
P5	56	M	IVA	B2	SS	CD3⁺ CD4⁺ CD7⁺CD26⁻ CD2dim⁺ CD8⁻ CD5⁺ CD25⁻	60.1	973.6	ECP, BEX
P6	85	M	IVA	B2	SS	CD3⁺ CD4⁺ CD7dim/⁻ CD26⁻ CD2Var⁺ CD8⁻ CD5⁺	74.1	1387.2	ECP, BEX
P7	78	F	IVA	B2	SS	CD3⁺CD4⁺CD7⁻CD26⁻CD5⁺CD8⁻	42.3	802.0	ECP, BEX, VRS
P8	74	F	IVA	B2	SS	CD3⁺ CD4⁺ CD7⁺CD26⁻CD8⁻	89.0	979.0	Moga
P9	68	F	IVA	B1	SS	CD3dim⁺ CD4dim⁺CD7⁻ CD26dim/⁻ CD2dim⁺CD8⁻ CD10⁻ CD5dim⁺ CD25⁻	51.9	356.2	ECP, BEX, IFN-α, IFN-γ
P10	70	M	IIB	B1	MF	CD3⁺ CD4⁺ CD7^−/+ CD26⁻ CD5dim⁺	44.8	503.9	ECP, BEX
P11	76	M	IIB	B1	MF	CD3dim⁺ CD4dim⁺ CD7⁻ CD26⁻ CD5⁺	58.0	580.0	ECP, BEX, IFN-α

Sample ID	Age	Sex	ISCL stage	B stage	CTCL subtype	Clinically abnormal phenotype	% CD4⁺CD26⁻	Abs. abn.∗ (/μL)	Treatment
P1	81	M	IVA	B2	SS	CD3dim⁺ CD4⁺ CD7⁻ CD26⁻ CD2⁺ CD8⁻ CD10⁻ CD5⁺	87.8	1818.3	ECP, ACIT
P2	76	M	IIB	B1	MF	CD3dim⁺ CD4⁺ CD7⁻ CD26⁻ CD8⁻ CD5⁺ CD2⁺	37.4	1774.6	ECP, BEX
P3	72	F	IVA	B2	SS	CD3⁺ CD4⁺ CD7Var⁺ CD26⁻ CD8⁻ CD2⁺ CD25⁻	82.6	2799.6	ECP, BEX, IFN-α
P4	79	M	IA	B1	MF	CD3dim⁺ CD4⁺ CD7⁻ CD26⁻ CD2⁺	61.2	964.5	ECP, BEX
P5	56	M	IVA	B2	SS	CD3⁺ CD4⁺ CD7⁺CD26⁻ CD2dim⁺ CD8⁻ CD5⁺ CD25⁻	60.1	973.6	ECP, BEX
P6	85	M	IVA	B2	SS	CD3⁺ CD4⁺ CD7dim/⁻ CD26⁻ CD2Var⁺ CD8⁻ CD5⁺	74.1	1387.2	ECP, BEX
P7	78	F	IVA	B2	SS	CD3⁺CD4⁺CD7⁻CD26⁻CD5⁺CD8⁻	42.3	802.0	ECP, BEX, VRS
P8	74	F	IVA	B2	SS	CD3⁺ CD4⁺ CD7⁺CD26⁻CD8⁻	89.0	979.0	Moga
P9	68	F	IVA	B1	SS	CD3dim⁺ CD4dim⁺CD7⁻ CD26dim/⁻ CD2dim⁺CD8⁻ CD10⁻ CD5dim⁺ CD25⁻	51.9	356.2	ECP, BEX, IFN-α, IFN-γ
P10	70	M	IIB	B1	MF	CD3⁺ CD4⁺ CD7^−/+ CD26⁻ CD5dim⁺	44.8	503.9	ECP, BEX
P11	76	M	IIB	B1	MF	CD3dim⁺ CD4dim⁺ CD7⁻ CD26⁻ CD5⁺	58.0	580.0	ECP, BEX, IFN-α

ISCL stage and B stage are at diagnosis, and blood counts and treatments are at the time of sequencing.

Abs. abn., absolute numbers of abnormal cells; ACIT, acitretin; BEX, bexarotene; ECP, extracorporeal photopheresis; IFN-α, interferon-α; ISCL, International Society for Cutaneous Lymphomas; Lymph, lymphocytes; Moga, mogamulizumab; VRS, Vorinostat; WBC, white blood cell.

∗

Abs. abn. = (% CD4⁺CD26⁻ × % lymph.)/10 000 × WBC × 1000.

View Large