Frequency of autoantibody detection
| Characteristic . | Patients with AHA (N = 69) . | Controls (N = 69) . | OR (95% CI) . | P . |
|---|---|---|---|---|
| ANA (positive ≥ 1:160), n (%) | 44 (64) | 21 (30) | 4.02 (2.02-8.01) | .0002 |
| ANA staining pattern | ||||
| Homogenous, n/n (%) | 7/44 (16) | 7/21 (33) | ||
| Speckled, n/n (%) | 31/44 (70) | 13/21 (62) | ||
| Other, n/n (%) | 6/44 (14) | 1/21 (5) | ||
| Cytoplasmic, n (%) | 21 (30) | 13 (19) | 1.88 (0.85-4.16) | .166 |
| ENA, n (%) | 4 (6) | 2 (3) | 2.06 (0.46-11) | .680 |
| dsDNA, n (%) | 2 (3) | 3 (4) | 0.66 (0.11-3.31) | .999 |
| AF IgG, n (%) | 8 (12) | 10 (14) | 0.77 (0.28-2.00) | .801 |
| AF IgA, n (%) | 8 (12) | 0 (0) | Infinite (2.34-+∞) | .006 |
| Any of the above, n (%) | 54 (78) | 32 (46) | 4.16 (1.98-8.39) | .0002 |
| Characteristic . | Patients with AHA (N = 69) . | Controls (N = 69) . | OR (95% CI) . | P . |
|---|---|---|---|---|
| ANA (positive ≥ 1:160), n (%) | 44 (64) | 21 (30) | 4.02 (2.02-8.01) | .0002 |
| ANA staining pattern | ||||
| Homogenous, n/n (%) | 7/44 (16) | 7/21 (33) | ||
| Speckled, n/n (%) | 31/44 (70) | 13/21 (62) | ||
| Other, n/n (%) | 6/44 (14) | 1/21 (5) | ||
| Cytoplasmic, n (%) | 21 (30) | 13 (19) | 1.88 (0.85-4.16) | .166 |
| ENA, n (%) | 4 (6) | 2 (3) | 2.06 (0.46-11) | .680 |
| dsDNA, n (%) | 2 (3) | 3 (4) | 0.66 (0.11-3.31) | .999 |
| AF IgG, n (%) | 8 (12) | 10 (14) | 0.77 (0.28-2.00) | .801 |
| AF IgA, n (%) | 8 (12) | 0 (0) | Infinite (2.34-+∞) | .006 |
| Any of the above, n (%) | 54 (78) | 32 (46) | 4.16 (1.98-8.39) | .0002 |
The number of patients with a positive result according to central laboratory cutoff. ANA and cytoplasmic antibodies were detected in HEp-2 immunofluorescence; other antibodies were detected using an enzyme immunoassay.