Frailty scoring/outcome scoring systems myeloma patients
| Score . | Reference . | Variables . | Frailty/outcome groups defined . |
|---|---|---|---|
| Transplant assessment scoring systems | |||
| HCT-CI | 5 | Based on criteria reported by Sorror et al49 | 0 1-2 >2 |
| Frailty scoring/outcome scoring systems for transplant-ineligible patients | |||
| IMWG* | 16 | Age CCI IADL ADL | Fit Intermediate-fit Frail |
| Simplified IMWG | 89 | Age CCI ECOG | Nonfrail Frail |
| R-MCI | 90 | Age eGFR Lung disease KPS Frailty Cytogenetics | Fit Intermediate-fit Frail |
| UK MRP | 91 | Age PS CRP ISS | Low risk Medium risk High risk |
| Mayo frailty | 92 | Age PS NT-BNP | I II III IV |
| Objective and patient-reported outcome measures | |||
| Objective measures | |||
| Timed up and go85 | Subjects rise from a standard armchair, walk 3 meters, walk back, and sit down again | ||
| Hand grip strength93 | Measured using a dynamometer (static force hand can squeeze around a dynamometer) | ||
| Short Physical Performance Battery94 | Combines gait speed, chair stand, and balance tests | ||
| Score . | Reference . | Variables . | Frailty/outcome groups defined . |
|---|---|---|---|
| Transplant assessment scoring systems | |||
| HCT-CI | 5 | Based on criteria reported by Sorror et al49 | 0 1-2 >2 |
| Frailty scoring/outcome scoring systems for transplant-ineligible patients | |||
| IMWG* | 16 | Age CCI IADL ADL | Fit Intermediate-fit Frail |
| Simplified IMWG | 89 | Age CCI ECOG | Nonfrail Frail |
| R-MCI | 90 | Age eGFR Lung disease KPS Frailty Cytogenetics | Fit Intermediate-fit Frail |
| UK MRP | 91 | Age PS CRP ISS | Low risk Medium risk High risk |
| Mayo frailty | 92 | Age PS NT-BNP | I II III IV |
| Objective and patient-reported outcome measures | |||
| Objective measures | |||
| Timed up and go85 | Subjects rise from a standard armchair, walk 3 meters, walk back, and sit down again | ||
| Hand grip strength93 | Measured using a dynamometer (static force hand can squeeze around a dynamometer) | ||
| Short Physical Performance Battery94 | Combines gait speed, chair stand, and balance tests | ||
ADL, activities of daily living; CCI, Charleson Comorbidity Index; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; IADL, instrumental activities of daily living; ISS, International Scoring System; KPS, Karnofsky Performance Scale; MRP, UK Myeloma Research Alliance Risk Profile; NT-BNP, B-natriuretic peptide; PS, performance status; R-MCI, revised Myeloma Comorbidity Index.