Systemic staging/work-up- -
Physical examination - -
Age - -
Performance status (Karnofsky Performance Scale or Eastern Cooperative Oncology Group Performance Status) - -
HIV status - -
LDH - -
Hepatic and renal function - -
Bone marrow biopsy - -
PET/CT chest/abdomen/pelvis - -
Testicular ultrasound (men)
Neurological staging- -
MRI brain with/without gadolinium contrast - -
MRI total spine with/without gadolinium contrast - -
Lumbar tap (CSF cell count, protein, glucose, cytology, flow cytometry, immunoglobulin heavy chain gene rearrangement - -
Ophthalmologic examination (both eyes; with slit lamp)
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