Table 2.

Multivariate analysis of factors associated with PFS

Patients (N = 54)Median PFS (wk)P, univariateHR95% CIP, multivariate
BM involvement .001 5.2 1.8-15 .003 
No BM involvement 12     
Prior CNS involvement .01 – – .23 
No prior CNS involvement 10     
Elevated LDH .001 1.4-16 .01 
No elevated LDH NR     
Patients (N = 54)Median PFS (wk)P, univariateHR95% CIP, multivariate
BM involvement .001 5.2 1.8-15 .003 
No BM involvement 12     
Prior CNS involvement .01 – – .23 
No prior CNS involvement 10     
Elevated LDH .001 1.4-16 .01 
No elevated LDH NR     

CNS, central nervous system; HR, hazard ratio; LDH, lactate dehydrogenase.

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