Leukemia-free survival by risk group in the training and validation subsets
| . | Training subset . | Validation subset Brier score* . | ||||
|---|---|---|---|---|---|---|
| Risk group . | n . | HR (95% CI) . | P . | n . | HR (95% CI) . | P . |
| AML | ||||||
| Low | 34 | 1.00 | <.0001 | 29 | 1.00 | <.0001 |
| Intermediate | 291 | 1.91 (0.93-3.91) | .0764 | 308 | 3.05 (1.25-7.45) | .0114 |
| High | 144 | 3.22 (1.56-6.662) | .0016 | 138 | 4.87 (1.97-12.02) | .0006 |
| Very high | 93 | 5.65 (2.72-11.73) | <.0001 | 92 | 8.10 (3.26-20.11) | <.0001 |
| ALL | ||||||
| Low | 238 | 1.00 | <.0001 | 227 | 1.00 | <.0001 |
| Intermediate | 364 | 1.56 (1.19-2.04) | .0014 | 379 | 1.72 (1.29-2.28) | .0002 |
| High | 42 | 2.90 (1.88-4.48) | <.0001 | 30 | 3.55 (2.15-5.85) | <.0001 |
| . | Training subset . | Validation subset Brier score* . | ||||
|---|---|---|---|---|---|---|
| Risk group . | n . | HR (95% CI) . | P . | n . | HR (95% CI) . | P . |
| AML | ||||||
| Low | 34 | 1.00 | <.0001 | 29 | 1.00 | <.0001 |
| Intermediate | 291 | 1.91 (0.93-3.91) | .0764 | 308 | 3.05 (1.25-7.45) | .0114 |
| High | 144 | 3.22 (1.56-6.662) | .0016 | 138 | 4.87 (1.97-12.02) | .0006 |
| Very high | 93 | 5.65 (2.72-11.73) | <.0001 | 92 | 8.10 (3.26-20.11) | <.0001 |
| ALL | ||||||
| Low | 238 | 1.00 | <.0001 | 227 | 1.00 | <.0001 |
| Intermediate | 364 | 1.56 (1.19-2.04) | .0014 | 379 | 1.72 (1.29-2.28) | .0002 |
| High | 42 | 2.90 (1.88-4.48) | <.0001 | 30 | 3.55 (2.15-5.85) | <.0001 |
n, number evaluable.
AML, 0.154; ALL, 0.152.