Table 3.

Platelet counts pre– and post–SARS-CoV-2 vaccination in patients with preexisting ITP

Median [IQR], or n (%)N
Dose 1   
 Platelet count prevaccination (×109/L) 101 [60-199] 109 
 Timing of prevaccination platelet count(d)) 14 [4.5-34] 93 
 Platelet count at first post-vaccine assessment (×109/L)* 100 [50.5-195] 109 
 Timing of first postvaccination platelet count (d) 6 [4-9] 99 
 Timing of platelet nadir (d) 6 [4.8-9.3] 30 
 Platelet count nadir (×109/L) 46.8 [27.8-93.3] 34 
 Platelet count 11-29 ×109/L 7 (20.6) 34 
 Platelet count ≤10 ×109/L 3 (8.8) 34 
Dose 2   
 Platelet count prevaccination (×109/L) 101 [59.8-186] 70 
 Timing of prevaccination platelet count (d) 11.5 [3-30] 64 
 Platelet count at first postvaccine assessment (×109/L) 105.5 [52.8-202] 70 
 Timing of first postvaccination platelet count (d) 5 [3-7.5] 69 
 Timing of platelet nadir (d) 5 [2.5-8.5] 21 
 Platelet count nadir (×109/L) 34 [10.5-116] 21 
 Platelet count 11-30 ×109/L 5 (22.7) 21 
 Platelet count ≤10 ×109/L 5 (23.8) 21 
Median [IQR], or n (%)N
Dose 1   
 Platelet count prevaccination (×109/L) 101 [60-199] 109 
 Timing of prevaccination platelet count(d)) 14 [4.5-34] 93 
 Platelet count at first post-vaccine assessment (×109/L)* 100 [50.5-195] 109 
 Timing of first postvaccination platelet count (d) 6 [4-9] 99 
 Timing of platelet nadir (d) 6 [4.8-9.3] 30 
 Platelet count nadir (×109/L) 46.8 [27.8-93.3] 34 
 Platelet count 11-29 ×109/L 7 (20.6) 34 
 Platelet count ≤10 ×109/L 3 (8.8) 34 
Dose 2   
 Platelet count prevaccination (×109/L) 101 [59.8-186] 70 
 Timing of prevaccination platelet count (d) 11.5 [3-30] 64 
 Platelet count at first postvaccine assessment (×109/L) 105.5 [52.8-202] 70 
 Timing of first postvaccination platelet count (d) 5 [3-7.5] 69 
 Timing of platelet nadir (d) 5 [2.5-8.5] 21 
 Platelet count nadir (×109/L) 34 [10.5-116] 21 
 Platelet count 11-30 ×109/L 5 (22.7) 21 
 Platelet count ≤10 ×109/L 5 (23.8) 21 
*

Does not include 2 patients with “normal” platelet count.

Includes only patients with decrease >20% in platelet count.

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