Table 2. Toxicity summary by grade per... | American Society of Hematology

Table 2.

Toxicity summary by grade per Bearman criteria

Organ	DL1: 5 mg (d +60) (n = 3)				DL1: 5 mg (d +45) (n = 3)				DL2: 10 mg (d +45) (n = 12)
Organ	1	2	3	4	1	2	3	4	1	2	3	4
Bladder	0	0	0	0	0	0	0	0	2	0	0	0
Cardiac	0	0	1*	0	0	0	0	0	4	0	0	0
CNS	0	1	0	0	0	0	0	0	2	1	0	0
GI	2	0	1*	0	2	0	0	0	9	0	0	0
Hepatic	1	1	0	0	0	0	0	0	1	0	0	0
Pulmonary	1	0	0	1*	0	0	0	0	4	2	0	0
Renal	2	0	0	0	0	0	0	0	5	2	1*	0
Stomatitis	3	0	0	0	3	0	0	0	6	2	0	0

Organ	DL1: 5 mg (d +60) (n = 3)				DL1: 5 mg (d +45) (n = 3)				DL2: 10 mg (d +45) (n = 12)
Organ	1	2	3	4	1	2	3	4	1	2	3	4
Bladder	0	0	0	0	0	0	0	0	2	0	0	0
Cardiac	0	0	1*	0	0	0	0	0	4	0	0	0
CNS	0	1	0	0	0	0	0	0	2	1	0	0
GI	2	0	1*	0	2	0	0	0	9	0	0	0
Hepatic	1	1	0	0	0	0	0	0	1	0	0	0
Pulmonary	1	0	0	1*	0	0	0	0	4	2	0	0
Renal	2	0	0	0	0	0	0	0	5	2	1*	0
Stomatitis	3	0	0	0	3	0	0	0	6	2	0	0

First 3 patients at DL1 were followed for DLTs until d +60 posttransplantation. The remaining patients were followed for DLTs for 45 d after transplantation.

CNS, central nervous system; GI, gastrointestinal.

DLT.

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