Table 1.

Baseline characteristics of the 47 patients with nonmeasurable multiple myeloma who had sufficient residual serum for MALDI-TOF MS testing

Clinical parameterNo. of patients (%)
NSMM (n = 22)  
 Normal FLC ratio 8 (36.4) 
 iFLC < 50 mg/L with abnormal FLC ratio 7 (31.8) 
 iFLC 50-100 mg/L with abnormal FLC ratio 7 (31.8) 
Urinary light chains  
 <200 mg/g creatinine (range 0-70 mg/g creatinine) 18 (81.8) 
 Missing 4 (18.2) 
Immune paresis 17 (77.3) 
Serum creatinine <177 μmol/L 22 (100) 
ISS  
 1 16 (72.7) 
 2 4 (18.2) 
 3 2 (9.1) 
OSMM (n = 25)  
 IgG monoclonal protein 13 (52.0) 
 IgA monoclonal protein 10 (40.0) 
 Light chain only 1 (4.0) 
 Biclonal 1 (4.0) 
 Monoclonal protein <5 g/L (range 0-4.11 g/L) 8 (32.0) 
 Monoclonal protein 5 to <10 g/L (range 5.0-9.3 g/L) 17 (68.0) 
 Normal FLC ratio 4 (16.0) 
 iFLC < 50 mg/L with abnormal FLC ratio 17 (68.0) 
 iFLC 50-100 mg/L with abnormal FLC ratio 4 (16.0) 
 Immune paresis 21 (84.0) 
 Serum creatinine <177 μmol/L 25 (100) 
ISS  
 1 17 (68.0) 
 2 6 (24.0) 
 3 1 (4.0) 
 Missing 1 (4.0) 
Clinical parameterNo. of patients (%)
NSMM (n = 22)  
 Normal FLC ratio 8 (36.4) 
 iFLC < 50 mg/L with abnormal FLC ratio 7 (31.8) 
 iFLC 50-100 mg/L with abnormal FLC ratio 7 (31.8) 
Urinary light chains  
 <200 mg/g creatinine (range 0-70 mg/g creatinine) 18 (81.8) 
 Missing 4 (18.2) 
Immune paresis 17 (77.3) 
Serum creatinine <177 μmol/L 22 (100) 
ISS  
 1 16 (72.7) 
 2 4 (18.2) 
 3 2 (9.1) 
OSMM (n = 25)  
 IgG monoclonal protein 13 (52.0) 
 IgA monoclonal protein 10 (40.0) 
 Light chain only 1 (4.0) 
 Biclonal 1 (4.0) 
 Monoclonal protein <5 g/L (range 0-4.11 g/L) 8 (32.0) 
 Monoclonal protein 5 to <10 g/L (range 5.0-9.3 g/L) 17 (68.0) 
 Normal FLC ratio 4 (16.0) 
 iFLC < 50 mg/L with abnormal FLC ratio 17 (68.0) 
 iFLC 50-100 mg/L with abnormal FLC ratio 4 (16.0) 
 Immune paresis 21 (84.0) 
 Serum creatinine <177 μmol/L 25 (100) 
ISS  
 1 17 (68.0) 
 2 6 (24.0) 
 3 1 (4.0) 
 Missing 1 (4.0) 

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