Sociodemographic factors associated with access to allogeneic HCT
| Referencea . | Population . | Access variable(s) . | Key findings . |
|---|---|---|---|
| Jabo et al3 | Age ≥15 years; patients with ALL/AML in California Cancer Registry; 2003-2012 | Age, race/ethnicity, geography, SES | Higher rate of HCT in patients aged ≤40 and in married patients; women more likely to receive HCT for ALL; lower rates of HCT in Hispanic and non-Hispanic Black patients; no association between distance and HCT utilization; low neighborhood quintile SES index associated with less utilization of HCT |
| Dehn et al10 | All ages; donor searches through Be the Match registry; 2016 | Race/ethnicity | White patients more likely to receive HCT compared to Black patients |
| Barker et al12 | Age ≤70 years; single-center study of patients undergoing unrelated donor search; 2005-2017 | Race/ethnicity | Patients of European ancestry more likely to receive 8/8 HLA-MUD HCT transplant than non-European ancestry and less likely to have no MUD or cord-blood grafts |
| Bhatt et al2 | Age 61-75 years; National Cancer Database, patients with AML; 2003-2012 | Age, race/ethnicity, geography, SES, insurance coverage | Lower likelihood of receiving HCT in patients who were older, non-White, of lower educational status, uninsured, on Medicaid/Medicare, or received care at nonacademic facility; no difference in HCT rates among urban vs rural facility; higher likelihood of receiving HCT in patients who lived ≥37 miles from facility; no association with median household income |
| Paulson et al5 | Age <66 years; patients with AML/ALL/MDS reported to CIBMTR and SEER; 2000-2010 | SES, geography | Higher county levels of poverty associated with lower transplant rates; rural vs urban status was not associated with HCT utilization |
| Delamater and Uberti18 | All ages; several public databases | Geography | Overall, 66% of US population lives within 60 minutes' travel time and 94% within 3 hours' travel time of HCT facility; geographic access to HCT facility varies by state |
| Getta et al27 | Age ≤70 years; single-center study of MDS patients; 2008-2015 | Age | Patients ≥65 years were less likely to be referred for HCT evaluation; marital status and insurance type were not associated with transplant referral |
| Referencea . | Population . | Access variable(s) . | Key findings . |
|---|---|---|---|
| Jabo et al3 | Age ≥15 years; patients with ALL/AML in California Cancer Registry; 2003-2012 | Age, race/ethnicity, geography, SES | Higher rate of HCT in patients aged ≤40 and in married patients; women more likely to receive HCT for ALL; lower rates of HCT in Hispanic and non-Hispanic Black patients; no association between distance and HCT utilization; low neighborhood quintile SES index associated with less utilization of HCT |
| Dehn et al10 | All ages; donor searches through Be the Match registry; 2016 | Race/ethnicity | White patients more likely to receive HCT compared to Black patients |
| Barker et al12 | Age ≤70 years; single-center study of patients undergoing unrelated donor search; 2005-2017 | Race/ethnicity | Patients of European ancestry more likely to receive 8/8 HLA-MUD HCT transplant than non-European ancestry and less likely to have no MUD or cord-blood grafts |
| Bhatt et al2 | Age 61-75 years; National Cancer Database, patients with AML; 2003-2012 | Age, race/ethnicity, geography, SES, insurance coverage | Lower likelihood of receiving HCT in patients who were older, non-White, of lower educational status, uninsured, on Medicaid/Medicare, or received care at nonacademic facility; no difference in HCT rates among urban vs rural facility; higher likelihood of receiving HCT in patients who lived ≥37 miles from facility; no association with median household income |
| Paulson et al5 | Age <66 years; patients with AML/ALL/MDS reported to CIBMTR and SEER; 2000-2010 | SES, geography | Higher county levels of poverty associated with lower transplant rates; rural vs urban status was not associated with HCT utilization |
| Delamater and Uberti18 | All ages; several public databases | Geography | Overall, 66% of US population lives within 60 minutes' travel time and 94% within 3 hours' travel time of HCT facility; geographic access to HCT facility varies by state |
| Getta et al27 | Age ≤70 years; single-center study of MDS patients; 2008-2015 | Age | Patients ≥65 years were less likely to be referred for HCT evaluation; marital status and insurance type were not associated with transplant referral |
Table shows representative studies in US populations published since 2015.
MDS, myelodysplastic syndrome.