Table 3.

Cox proportional hazards model of association between gemtuzumab and survival among racial-ethnic and cytogenetic subgroups

Cytogenetic subgroup
Race-ethnicity
Event free survival
HR (95% CI)
Overall survival
HR (95% CI)
All cytogenetic groups   
 All patients 0.84 (0.69-1.03) 0.91 (0.71-1.16) 
 Black 0.62 (0.38-1.03) 0.57 (0.33-0.99) 
 Hispanic 0.99 (0.63-1.55) 0.94 (0.56-1.57) 
 WNH 0.85 (0.66-1.10) 1.01 (0.74-1.39) 
KMT2Ar AML   
 All patients 0.64 (0.43-0.95) 0.78 (0.48-1.27) 
 Black 0.67 (0.24-1.86) 0.36 (0.12-1.06) 
 Hispanic 0.42 (0.15-1.18) 0.84 (0.25-2.81) 
 WNH 0.60 (0.36-0.98) 0.79 (0.42-1.46) 
Core binding factor AML   
 All patients 0.79 (0.50-1.24) 1.00 (0.53-1.87) 
 Black 0.30 (0.10-0.92) 0.44 (0.12-1.64) 
 Hispanic 1.66 (0.63-4.35) 1.19 (0.40-3.54) 
 WNH 0.75 (0.42-1.35) 1.22 (0.47-3.22) 
Cytogenetic subgroup
Race-ethnicity
Event free survival
HR (95% CI)
Overall survival
HR (95% CI)
All cytogenetic groups   
 All patients 0.84 (0.69-1.03) 0.91 (0.71-1.16) 
 Black 0.62 (0.38-1.03) 0.57 (0.33-0.99) 
 Hispanic 0.99 (0.63-1.55) 0.94 (0.56-1.57) 
 WNH 0.85 (0.66-1.10) 1.01 (0.74-1.39) 
KMT2Ar AML   
 All patients 0.64 (0.43-0.95) 0.78 (0.48-1.27) 
 Black 0.67 (0.24-1.86) 0.36 (0.12-1.06) 
 Hispanic 0.42 (0.15-1.18) 0.84 (0.25-2.81) 
 WNH 0.60 (0.36-0.98) 0.79 (0.42-1.46) 
Core binding factor AML   
 All patients 0.79 (0.50-1.24) 1.00 (0.53-1.87) 
 Black 0.30 (0.10-0.92) 0.44 (0.12-1.64) 
 Hispanic 1.66 (0.63-4.35) 1.19 (0.40-3.54) 
 WNH 0.75 (0.42-1.35) 1.22 (0.47-3.22) 

Statistically significant values are bolded.

WNH, White non-Hispanic

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