Table 2.

PVI by disease category

At initial assessmentAt final assessment
DiagnosisPVIPVI scorePVIPVI score
(Continuous; median, IQR)(0-6; median, IQR)(Continuous; median, IQR)(0-6; median, IQR)
ITP (entire cohort) 0.5 (−8.1, 8.9) 3 (1, 5) 6.4 (−2.9, 10.7) 4 (2, 5) 
Definite ITP 8.9 (5.8, 11.0) 5 (4, 5) 11.1 (9.7, 12.7) 5 (5, 6) 
Possible ITP −1.1 (−10.3, 7.3) 2 (0, 4) 3.0 (−5.6, 9.0) 3 (1, 5) 
Non-immune TCP −14.3 (−21.7, −4.9) 0 (0, 2) −10.5 (−18.8, −1.6) 0 (0, 2) 
Splenomegaly −14.1 (−18.9, −5.6) 0 (0, 1.5) −9.8 (−16.6, −2.6) 1 (0, 2) 
Liver disease −8.5 (−10.2, 1.5) 1 (0, 3) −0.9 (−4.7, 2.1) 2 (2, 3) 
Familial TCP −11.7 (−17.4, −4.5) 0 (0, 2) −7.0 (−12.0, −2.0) 1 (0, 2) 
MDS -1.5 (−11.0, 2.1) 2 (0.8, 3) 1.7 (−1.9, 4.4) 3 (2, 3) 
At initial assessmentAt final assessment
DiagnosisPVIPVI scorePVIPVI score
(Continuous; median, IQR)(0-6; median, IQR)(Continuous; median, IQR)(0-6; median, IQR)
ITP (entire cohort) 0.5 (−8.1, 8.9) 3 (1, 5) 6.4 (−2.9, 10.7) 4 (2, 5) 
Definite ITP 8.9 (5.8, 11.0) 5 (4, 5) 11.1 (9.7, 12.7) 5 (5, 6) 
Possible ITP −1.1 (−10.3, 7.3) 2 (0, 4) 3.0 (−5.6, 9.0) 3 (1, 5) 
Non-immune TCP −14.3 (−21.7, −4.9) 0 (0, 2) −10.5 (−18.8, −1.6) 0 (0, 2) 
Splenomegaly −14.1 (−18.9, −5.6) 0 (0, 1.5) −9.8 (−16.6, −2.6) 1 (0, 2) 
Liver disease −8.5 (−10.2, 1.5) 1 (0, 3) −0.9 (−4.7, 2.1) 2 (2, 3) 
Familial TCP −11.7 (−17.4, −4.5) 0 (0, 2) −7.0 (−12.0, −2.0) 1 (0, 2) 
MDS -1.5 (−11.0, 2.1) 2 (0.8, 3) 1.7 (−1.9, 4.4) 3 (2, 3) 

PVI scores and associated PVI values: 0 (–∞, –10); 1 (–10, –5); 2 (−5, 0); 3, (0, 5); 4 (5, 8); 5 (8, 12); 6 (12, +∞). Brackets are inclusive of the value limit.

MDS, myelodysplastic syndrome; TCP, thrombocytopenia.

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