Comparison of percentages of B-cell subsets in lymphocytes between patients with ITP and HCs
| B-cell subset . | BM (%) . | PB (%) . | ||||
|---|---|---|---|---|---|---|
| Patients with ITP . | HCs . | P . | Patients with ITP . | HCs . | P . | |
| Immature B | 0.22 ± 0.07 | 0.53 ± 0.12 | .029 | |||
| Naive B | 4.66 ± 0.66 | 12.52 ± 1.75 | <.001 | 4.95 ± 0.61 | 3.16 ± 0.38 | .027 |
| Memory B | 1.52 ± 0.25 | 1.51 ± 0.24 | .992 | 1.28 ± 0.22 | 1.14 ± 0.27 | .693 |
| Plasmablast | 0.06 ± 0.03 | 0.07 ± 0.03 | .782 | 0.06 ± 0.01 | 0.05 ± 0.02 | .617 |
| SLPC | 0.79 ± 0.26 | 1.03 ± 0.26 | .543 | 0.018 ± 0.005 | 0.016 ± 0.008 | .843 |
| Breg | 0.58 ± 0.15 | 2.84 ± 0.34 | <.001 | 0.05 ± 0.01 | 0.18 ± 0.04 | .004 |
| B-cell subset . | BM (%) . | PB (%) . | ||||
|---|---|---|---|---|---|---|
| Patients with ITP . | HCs . | P . | Patients with ITP . | HCs . | P . | |
| Immature B | 0.22 ± 0.07 | 0.53 ± 0.12 | .029 | |||
| Naive B | 4.66 ± 0.66 | 12.52 ± 1.75 | <.001 | 4.95 ± 0.61 | 3.16 ± 0.38 | .027 |
| Memory B | 1.52 ± 0.25 | 1.51 ± 0.24 | .992 | 1.28 ± 0.22 | 1.14 ± 0.27 | .693 |
| Plasmablast | 0.06 ± 0.03 | 0.07 ± 0.03 | .782 | 0.06 ± 0.01 | 0.05 ± 0.02 | .617 |
| SLPC | 0.79 ± 0.26 | 1.03 ± 0.26 | .543 | 0.018 ± 0.005 | 0.016 ± 0.008 | .843 |
| Breg | 0.58 ± 0.15 | 2.84 ± 0.34 | <.001 | 0.05 ± 0.01 | 0.18 ± 0.04 | .004 |
BM, bone marrow; HCs, healthy controls; ITP, immune thrombocytopenia; PB, peripheral blood; SLPC, short-lived plasma cell.