Baseline characteristics, stratified by weight class
| . | Normal weight (n = 181) . | Overweight (n = 239) . | Obese (n = 237) . |
|---|---|---|---|
| Demographic characteristics | |||
| Age, mean (standard deviation) | 58.1 (18.7) | 63 (15) | 59 (14.4) |
| Female sex, % (n) | 42.5 (77) | 41.4 (99) | 44.3 (105) |
| VTE-related risk factors | |||
| Active cancer, % (n) | 15.6 (28) | 12.8 (30) | 8.1 (19) |
| History of VTE, % (n) | 28.1 (50) | 23.5 (54) | 35.4 (80) |
| Recent surgery, % (n) | 6.1 (11) | 7.7 (18) | 7.4 (17) |
| Recent trauma, % (n) | 4.5 (8) | 4.7 (11) | 4.4 (10) |
| Recent immobilization, % (n) | 17.2 (31) | 16.8 (39) | 15.5 (36) |
| Recent > 4-hour travel, % (n) | 14.6 (26) | 13.5 (31) | 10 (23) |
| Cardiovascular risk factors | |||
| Diabetes, % (n) | 3.9 (7) | 13.1 (30) | 21.1 (48) |
| Arterial hypertension, % (n) | 36 (64) | 49.8 (115) | 67.3 (152) |
| Current smoking, % (n) | 18.6 (33) | 14.3 (32) | 16.5 (36) |
| Cardiovascular disease | |||
| Atrial fibrillation, % (n) | 5.6 (10) | 4.4 (10) | 3.9 (9) |
| Heart failure, % (n) | 3.4 (6) | 5.8 (13) | 4.4 (10) |
| Coronary artery disease, % (n) | 6.7 (12) | 7 (16) | 8.2 (18) |
| Peripheral artery disease, % (n) | 6 (8) | 3.4 (5) | 3.6 (5) |
| History of stroke, % (n) | 4.5 (8) | 4.3 (10) | 6.1 (14) |
| Medication intake | |||
| Cardiovascular medication, % (n) | 57.9 (95) | 69.8 (148) | 73.2 (153) |
| Antithrombotic medication, % (n) | 91.5 (150) | 95.3 (202) | 92.8 (194) |
| NSAIDs, % (n) | 5.5 (9) | 4.7 (10) | 5.2 (12) |
| Corticosteroids, % (n) | 6.1 (10) | 14.2 (30) | 5.3 (11) |
| Contraceptives, % (n) | 7.9 (13) | 3.3 (7) | 3.3 (7) |
| Laboratory markers | |||
| D-dimer in mg/L, median (IQR) | 2.9 (1.3/7.2) | 3.9 (1.5/7.7) | 3.8 (1.6/7.5) |
| C-reactive protein in mg/L, median (IQR) | 12 (4.8/41) | 18 (4.7/45.5) | 18 (6.2/46.2) |
| . | Normal weight (n = 181) . | Overweight (n = 239) . | Obese (n = 237) . |
|---|---|---|---|
| Demographic characteristics | |||
| Age, mean (standard deviation) | 58.1 (18.7) | 63 (15) | 59 (14.4) |
| Female sex, % (n) | 42.5 (77) | 41.4 (99) | 44.3 (105) |
| VTE-related risk factors | |||
| Active cancer, % (n) | 15.6 (28) | 12.8 (30) | 8.1 (19) |
| History of VTE, % (n) | 28.1 (50) | 23.5 (54) | 35.4 (80) |
| Recent surgery, % (n) | 6.1 (11) | 7.7 (18) | 7.4 (17) |
| Recent trauma, % (n) | 4.5 (8) | 4.7 (11) | 4.4 (10) |
| Recent immobilization, % (n) | 17.2 (31) | 16.8 (39) | 15.5 (36) |
| Recent > 4-hour travel, % (n) | 14.6 (26) | 13.5 (31) | 10 (23) |
| Cardiovascular risk factors | |||
| Diabetes, % (n) | 3.9 (7) | 13.1 (30) | 21.1 (48) |
| Arterial hypertension, % (n) | 36 (64) | 49.8 (115) | 67.3 (152) |
| Current smoking, % (n) | 18.6 (33) | 14.3 (32) | 16.5 (36) |
| Cardiovascular disease | |||
| Atrial fibrillation, % (n) | 5.6 (10) | 4.4 (10) | 3.9 (9) |
| Heart failure, % (n) | 3.4 (6) | 5.8 (13) | 4.4 (10) |
| Coronary artery disease, % (n) | 6.7 (12) | 7 (16) | 8.2 (18) |
| Peripheral artery disease, % (n) | 6 (8) | 3.4 (5) | 3.6 (5) |
| History of stroke, % (n) | 4.5 (8) | 4.3 (10) | 6.1 (14) |
| Medication intake | |||
| Cardiovascular medication, % (n) | 57.9 (95) | 69.8 (148) | 73.2 (153) |
| Antithrombotic medication, % (n) | 91.5 (150) | 95.3 (202) | 92.8 (194) |
| NSAIDs, % (n) | 5.5 (9) | 4.7 (10) | 5.2 (12) |
| Corticosteroids, % (n) | 6.1 (10) | 14.2 (30) | 5.3 (11) |
| Contraceptives, % (n) | 7.9 (13) | 3.3 (7) | 3.3 (7) |
| Laboratory markers | |||
| D-dimer in mg/L, median (IQR) | 2.9 (1.3/7.2) | 3.9 (1.5/7.7) | 3.8 (1.6/7.5) |
| C-reactive protein in mg/L, median (IQR) | 12 (4.8/41) | 18 (4.7/45.5) | 18 (6.2/46.2) |
Normal weight was defined as BMI between 18.5 and 25 kg/m2; overweight as BMI ≥ 25 and <30 kg/m2, and obese as BMI of ≥30 kg/m2.