Multivariable model showing risk factors associated with hospitalization in children and adults
| Variable . | Hospitalization . | ||
|---|---|---|---|
| RR . | 95% CI . | P . | |
| Children | |||
| Hydroxyurea | 0.92 | 0.73-1.15 | .45 |
| Prior acute care visits for pain,* >2 vs 0 | 2.15 | 1.69-3.44 | <.0001 |
| SCD heart/lung† | 1.61 | 1.26-2.04 | .0001 |
| Adults | |||
| Hydroxyurea | 0.92 | 0.77-1.10 | .35 |
| Prior acute care visits for pain,* >2 vs 0 | 1.78 | 1.24-2.57 | .002 |
| Variable . | Hospitalization . | ||
|---|---|---|---|
| RR . | 95% CI . | P . | |
| Children | |||
| Hydroxyurea | 0.92 | 0.73-1.15 | .45 |
| Prior acute care visits for pain,* >2 vs 0 | 2.15 | 1.69-3.44 | <.0001 |
| SCD heart/lung† | 1.61 | 1.26-2.04 | .0001 |
| Adults | |||
| Hydroxyurea | 0.92 | 0.77-1.10 | .35 |
| Prior acute care visits for pain,* >2 vs 0 | 1.78 | 1.24-2.57 | .002 |
P < .05 was considered significant.
*Hospitalization and/or ED treat-and-release visit requiring IV opioids for pain in the last 3 years.
†Acute chest syndrome in the last 3 years and/or pulmonary hypertension.
None of the other covariates were significant (SCD brain, SCD renal, non-SCD neurobehavioral, non-SCD lung, non-SCD heart comorbidities).