Characteristics of VTE subjects and HCs
| . | Healthy controls . | VTE subjects . |
|---|---|---|
| Number | 87 | 115 |
| Age (mean ± SD), y | 35.6 ± 11.7 | 43.6 ± 11.6* |
| Female, n (%) | 45 (51.7) | 59 (51.3) |
| Mean BMI, kg/m2 ± SD | 26.9 ± 6.2 | 28.0 ± 5.5 |
| Overweight (BMI = 25-29.9 kg/m2), n (%) | 28 (32.2) | 45 (39.1) |
| Obese (BMI >30 kg/m2), n (%) | 23 (26.4) | 36 (31.3) |
| Hypertension, n (%) | 0 (0) | 11 (9.6) |
| History of smoking, n (%) | 0 (0) | 6 (5.2) |
| History of diabetes, n (%) | 8 (9.2) | 2 (1.7) |
| Receiving anticoagulant treatment, n (%) | 0 (0) | 74 (64.3) |
| VTE subjects with ≥1 IT, n (%) | NT | 40 (34.8) |
| Total number of ITs detected† | 45 | |
| FVL | NT | 25 (21.7) |
| PGM | NT | 13 (11.3) |
| PS | NT | 4 (3.5) |
| PC | NT | 1 (0.9) |
| AT | NT | 2 (1.7) |
| VTE subjects with >1 IT, n (%) | NT | 5 (4.4) |
| FH of VTE, n (%) | 3 (3.4) | 51 (44.3) |
| Positive FH and ≥1 IT, n (%) | 0 (0) | 19 (37.3) |
| Positive FH and no IT, n (%) | 0 (0) | 32 (62.7) |
| Anti-annexin A2 IgG, number positive/number assayed (%) | 1/60 (1.7) | 1/95 (1.1) |
| Anti-S100A10 IgG, number positive/number assayed (%) | 2/60 (3.3) | 0/95 (0) |
| . | Healthy controls . | VTE subjects . |
|---|---|---|
| Number | 87 | 115 |
| Age (mean ± SD), y | 35.6 ± 11.7 | 43.6 ± 11.6* |
| Female, n (%) | 45 (51.7) | 59 (51.3) |
| Mean BMI, kg/m2 ± SD | 26.9 ± 6.2 | 28.0 ± 5.5 |
| Overweight (BMI = 25-29.9 kg/m2), n (%) | 28 (32.2) | 45 (39.1) |
| Obese (BMI >30 kg/m2), n (%) | 23 (26.4) | 36 (31.3) |
| Hypertension, n (%) | 0 (0) | 11 (9.6) |
| History of smoking, n (%) | 0 (0) | 6 (5.2) |
| History of diabetes, n (%) | 8 (9.2) | 2 (1.7) |
| Receiving anticoagulant treatment, n (%) | 0 (0) | 74 (64.3) |
| VTE subjects with ≥1 IT, n (%) | NT | 40 (34.8) |
| Total number of ITs detected† | 45 | |
| FVL | NT | 25 (21.7) |
| PGM | NT | 13 (11.3) |
| PS | NT | 4 (3.5) |
| PC | NT | 1 (0.9) |
| AT | NT | 2 (1.7) |
| VTE subjects with >1 IT, n (%) | NT | 5 (4.4) |
| FH of VTE, n (%) | 3 (3.4) | 51 (44.3) |
| Positive FH and ≥1 IT, n (%) | 0 (0) | 19 (37.3) |
| Positive FH and no IT, n (%) | 0 (0) | 32 (62.7) |
| Anti-annexin A2 IgG, number positive/number assayed (%) | 1/60 (1.7) | 1/95 (1.1) |
| Anti-S100A10 IgG, number positive/number assayed (%) | 2/60 (3.3) | 0/95 (0) |