Demographic and baseline characteristics
| Characteristic . | Total SCD sample (n = 37)* . | SCD on hydroxyurea (n = 20) . | SCD not on hydroxyurea (n = 17) . | Non-SCD sample (n = 14) . |
|---|---|---|---|---|
| Sex, no. (%) | ||||
| Male | 18 (49) | 12 (60) | 6 (35) | 3 (21) |
| Female | 19 (51) | 8 (40) | 11 (65) | 11 (79) |
| Age, no. (%) | ||||
| 13-17 y | 12 (32.5) | 5 (25) | 7 (41) | 3 (22) |
| 18-27 y | 13 (35) | 9 (45) | 4 (24) | 2 (14) |
| 28-48 y | 12 (32.5) | 6 (30) | 6 (35) | 7 (50) |
| 49-63 y | 0 | 0 | 0 | 2 (14) |
| Ethnicity, no. (%) | ||||
| Hispanic | 1 (3) | 1 (5) | 0 | 0 |
| Non-Hispanic | 36 (97) | 19 (95) | 17 (100) | 14 (100) |
| Genotype, no. (%) | ||||
| HbSS | 31 (84) | 18 (90) | 13 (76) | NA |
| HbS-β0 thalassemia | 6 (16) | 2 (10) | 4 (24) | NA |
| SC trait | NA | NA | NA | 10 (71) |
| Characteristic . | Total SCD sample (n = 37)* . | SCD on hydroxyurea (n = 20) . | SCD not on hydroxyurea (n = 17) . | Non-SCD sample (n = 14) . |
|---|---|---|---|---|
| Sex, no. (%) | ||||
| Male | 18 (49) | 12 (60) | 6 (35) | 3 (21) |
| Female | 19 (51) | 8 (40) | 11 (65) | 11 (79) |
| Age, no. (%) | ||||
| 13-17 y | 12 (32.5) | 5 (25) | 7 (41) | 3 (22) |
| 18-27 y | 13 (35) | 9 (45) | 4 (24) | 2 (14) |
| 28-48 y | 12 (32.5) | 6 (30) | 6 (35) | 7 (50) |
| 49-63 y | 0 | 0 | 0 | 2 (14) |
| Ethnicity, no. (%) | ||||
| Hispanic | 1 (3) | 1 (5) | 0 | 0 |
| Non-Hispanic | 36 (97) | 19 (95) | 17 (100) | 14 (100) |
| Genotype, no. (%) | ||||
| HbSS | 31 (84) | 18 (90) | 13 (76) | NA |
| HbS-β0 thalassemia | 6 (16) | 2 (10) | 4 (24) | NA |
| SC trait | NA | NA | NA | 10 (71) |
HbS-β0, hemoglobin sickle-β; HbSS, hemoglobin SS; NA, not applicable.
Thirty-five participants completed the study.