Baseline characteristics of the relatives screened for and identified with MBL
. | Categories . | No. successfully screened (n = 1045) . | No. of those screened with MBL (n = 235, 22%) . |
---|---|---|---|
Sex | Male | 461 | 108 (23%) |
Female | 584 | 127 (22%) | |
Flow cytometry laboratory | Mayo | 399 | 113 (28%) |
Duke | 413 | 88 (21%) | |
US Food and Drug Administration | 233 | 34 (15%) | |
Age at first flow, y | Median (range) | 58 (40-101) | 65 (41-97) |
Age categories, y | 40-49 | 267 | 24 (9%) |
50-59 | 291 | 56 (19%) | |
60-69 | 230 | 62 (27%) | |
70-79 | 154 | 59 (38%) | |
≥80 | 69 | 32 (46%) | |
Missing | 34 | 2 | |
Dominant MBL type | CLL-like | 197 (84%) | |
Atypical | 18 (8%) | ||
Non–CLL-like | 20 (8%) | ||
Secondary MBL type (n = 11) | CLL-like | 8 | |
Atypical | 3 | ||
Absolute B-cell count, cells per μL (n = 114) | Median (range) | 126.7 (7.3-4099.8) | |
Absolute clonal B-cell count, cells per μL, CLL-like (n = 105) | Median (range) | 5.8 (0.3-4013.6) | |
Absolute clonal B-cell count, cells per μL, atypical | Median (range) | 22.5 (1.4-577.7) | |
Absolute clonal B-cell count, cells per μL, non–CLL-like | Median (range) | 61.5 (4.1-616.9) |
. | Categories . | No. successfully screened (n = 1045) . | No. of those screened with MBL (n = 235, 22%) . |
---|---|---|---|
Sex | Male | 461 | 108 (23%) |
Female | 584 | 127 (22%) | |
Flow cytometry laboratory | Mayo | 399 | 113 (28%) |
Duke | 413 | 88 (21%) | |
US Food and Drug Administration | 233 | 34 (15%) | |
Age at first flow, y | Median (range) | 58 (40-101) | 65 (41-97) |
Age categories, y | 40-49 | 267 | 24 (9%) |
50-59 | 291 | 56 (19%) | |
60-69 | 230 | 62 (27%) | |
70-79 | 154 | 59 (38%) | |
≥80 | 69 | 32 (46%) | |
Missing | 34 | 2 | |
Dominant MBL type | CLL-like | 197 (84%) | |
Atypical | 18 (8%) | ||
Non–CLL-like | 20 (8%) | ||
Secondary MBL type (n = 11) | CLL-like | 8 | |
Atypical | 3 | ||
Absolute B-cell count, cells per μL (n = 114) | Median (range) | 126.7 (7.3-4099.8) | |
Absolute clonal B-cell count, cells per μL, CLL-like (n = 105) | Median (range) | 5.8 (0.3-4013.6) | |
Absolute clonal B-cell count, cells per μL, atypical | Median (range) | 22.5 (1.4-577.7) | |
Absolute clonal B-cell count, cells per μL, non–CLL-like | Median (range) | 61.5 (4.1-616.9) |