Table 2.

Results of multivariate analysis adjusted for propensity score

OutcomeHR (95% CI)P
Grade 2-4 acute GVHD   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 0.44 (0.31-0.62) <.0001 
Grade 3-4 acute GVHD   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 0.26 (0.14-0.48) <.0001 
Chronic GVHD   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 0.36 (0.25-0.53) <.0001 
NRM*   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 0.90 (0.62-1.31) .57 
Relapse†   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 1.56 (1.14-2.14) .0055 
DFS‡   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 1.29 (1.01-1.65) .042 
OS§   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 0.94 (0.71-1.24) .65 
OutcomeHR (95% CI)P
Grade 2-4 acute GVHD   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 0.44 (0.31-0.62) <.0001 
Grade 3-4 acute GVHD   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 0.26 (0.14-0.48) <.0001 
Chronic GVHD   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 0.36 (0.25-0.53) <.0001 
NRM*   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 0.90 (0.62-1.31) .57 
Relapse†   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 1.56 (1.14-2.14) .0055 
DFS‡   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 1.29 (1.01-1.65) .042 
OS§   
 HLA-matched unrelated 1.00  
 HLA-haploidentical relative 0.94 (0.71-1.24) .65 

Each patient was assigned a propensity score based on age, KPS, HMAs before transplantation and IPSS-R score at transplantation.

HR, hazard ratio.

*

Adjusted for recipient CMV serostatus.

†

Adjusted for recipient sex.

‡

Adjusted for donor-recipient sex match.

§

Adjusted for HCT-CI score.

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