Patient characteristics
| Variable . | Total(n = 300) . | Abnormal karyotype(n = 204) . | Normal karyotype(n = 96) . | P . |
|---|---|---|---|---|
| Age | .316 | |||
| Median (range) | 55 (24-70) | 56 (25-70) | 54 (24-69) | |
| Sex | .314 | |||
| Male | 170 | 119 | 51 | |
| Female | 130 | 85 | 45 | |
| Disease type at diagnosis | <.001 | |||
| Acute | 183 | 129 | 56 | |
| Lymphoma | 70 | 55 | 15 | |
| Chronic | 33 | 16 | 15 | |
| Smoldering | 14 | 4 | 10 | |
| Conditioning regimens | .99 | |||
| MAC | 118 | 81 | 37 | |
| RIC | 182 | 123 | 59 | |
| Stem cell source | .887 | |||
| sib-BM | 31 | 21 | 10 | |
| sib-PB | 67 | 43 | 24 | |
| uBM | 137 | 96 | 41 | |
| uCB | 65 | 44 | 21 | |
| Samples | <.001 | |||
| PB | 41 | 34 | 7 | |
| BM | 166 | 84 | 82 | |
| Lymph node | 86 | 79 | 7 | |
| Others | 7 | 7 | 0 | |
| LDH level at diagnosis | .025 | |||
| Median, U/mL (range) | 487 (135-7 144) | 517.5 (169-7 144) | 424 (135-2 851) | |
| Level of sIL2R at diagnosis | .505 | |||
| Median, U/mL (range) | 17 969 (443.8-1 130 505) | 20 100 (443.8-254 000) | 14 798 (976-1 130 505) |
| Variable . | Total(n = 300) . | Abnormal karyotype(n = 204) . | Normal karyotype(n = 96) . | P . |
|---|---|---|---|---|
| Age | .316 | |||
| Median (range) | 55 (24-70) | 56 (25-70) | 54 (24-69) | |
| Sex | .314 | |||
| Male | 170 | 119 | 51 | |
| Female | 130 | 85 | 45 | |
| Disease type at diagnosis | <.001 | |||
| Acute | 183 | 129 | 56 | |
| Lymphoma | 70 | 55 | 15 | |
| Chronic | 33 | 16 | 15 | |
| Smoldering | 14 | 4 | 10 | |
| Conditioning regimens | .99 | |||
| MAC | 118 | 81 | 37 | |
| RIC | 182 | 123 | 59 | |
| Stem cell source | .887 | |||
| sib-BM | 31 | 21 | 10 | |
| sib-PB | 67 | 43 | 24 | |
| uBM | 137 | 96 | 41 | |
| uCB | 65 | 44 | 21 | |
| Samples | <.001 | |||
| PB | 41 | 34 | 7 | |
| BM | 166 | 84 | 82 | |
| Lymph node | 86 | 79 | 7 | |
| Others | 7 | 7 | 0 | |
| LDH level at diagnosis | .025 | |||
| Median, U/mL (range) | 487 (135-7 144) | 517.5 (169-7 144) | 424 (135-2 851) | |
| Level of sIL2R at diagnosis | .505 | |||
| Median, U/mL (range) | 17 969 (443.8-1 130 505) | 20 100 (443.8-254 000) | 14 798 (976-1 130 505) |
Data are the number of patients, unless stated otherwise. Statistically significant P values are in bold.
LDH, lactase dehydrogenase; sib-BM, bone marrow from sibling donor; sib-PB, peripheral blood from sibling donor; uBM, bone marrow from unrelated donor; uCB, cord blood from unrelated donor.