Staging of gastric MALT lymphoma: a comparison of staging systems and anatomic correlations
| Lugano staging system . | TNM (or Paris) staging system . | Disease extension . | |
|---|---|---|---|
| Stage I | I1: confined to mucosa or submucosa | T1 N0 M0 | Mucosal or submucosal layer |
| I2: confined to muscularis propria or serosa | T2 N0 M0 | Muscularis propria | |
| T3 N0 M0 | Serosa | ||
| Stage II | II1: extending into abdomen with local nodal involvement | T1-3 N1 M0 | Perigastric lymph nodes |
| II2: extending into abdomen with distant nodal involvement | T1-3 N2 M0 | More distant regional lymph nodes | |
| Stage IIE | Penetration of serosa to involve adjacent organs or tissues | T4 N0 M0 | Adjacent structures |
| Stage IV | Disseminated extranodal involvement or concomitant supradiaphragmatic involvement | T1-4 N3 M0 | Lymph nodes on both sides of the diaphragm |
| T1-4 N0-3 M1 | Bone marrow invasion, additional extranodal sites | ||
| Lugano staging system . | TNM (or Paris) staging system . | Disease extension . | |
|---|---|---|---|
| Stage I | I1: confined to mucosa or submucosa | T1 N0 M0 | Mucosal or submucosal layer |
| I2: confined to muscularis propria or serosa | T2 N0 M0 | Muscularis propria | |
| T3 N0 M0 | Serosa | ||
| Stage II | II1: extending into abdomen with local nodal involvement | T1-3 N1 M0 | Perigastric lymph nodes |
| II2: extending into abdomen with distant nodal involvement | T1-3 N2 M0 | More distant regional lymph nodes | |
| Stage IIE | Penetration of serosa to involve adjacent organs or tissues | T4 N0 M0 | Adjacent structures |
| Stage IV | Disseminated extranodal involvement or concomitant supradiaphragmatic involvement | T1-4 N3 M0 | Lymph nodes on both sides of the diaphragm |
| T1-4 N0-3 M1 | Bone marrow invasion, additional extranodal sites | ||