Table 2.

Platelet ABO compatibility

ABOPlatelet recipient ABO group
ABABO
Platelet donor ABO group AB Identical Major Major Major 
Minor Identical Bidirectional Major 
Minor Bidirectional Identical Major 
Minor Minor Minor Identical 
ABOPlatelet recipient ABO group
ABABO
Platelet donor ABO group AB Identical Major Major Major 
Minor Identical Bidirectional Major 
Minor Bidirectional Identical Major 
Minor Minor Minor Identical 
RhDPlatelet recipient RhD type
PositiveNegative
Platelet donor RhD type Positive Identical Mismatch 
At risk for RhD alloimmunization 
Negative Mismatch Identical 
No risk for RhD alloimmunization 
RhDPlatelet recipient RhD type
PositiveNegative
Platelet donor RhD type Positive Identical Mismatch 
At risk for RhD alloimmunization 
Negative Mismatch Identical 
No risk for RhD alloimmunization 

ABO identical: donor and recipient have the same ABO antigens and antibodies. Major ABO mismatch: donor ABO antigens are incompatible with recipient ABO antibodies. Minor ABO mismatch: donor ABO antibodies are incompatible with recipient's ABO antigens. ABO bidirectional mismatch: donor ABO antibodies are incompatible with recipient ABO antigens and donor ABO antigens are incompatible with recipient ABO antibodies. Rh mismatch: Rh type of the recipient is different from the Rh type of the donor. RhD-negative recipients of platelets obtained from RhD-positive donors are the only ones at risk for RhD alloimmunization.

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