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Journal Articles

Predicting secondary myeloid neoplasms in acquired aplastic anemia using machine learning models

Open Access
Ahmet Celal Toprak, Mutlu Mete, Julia J. Shi, Daria V. Babushok, Carmelo Gurnari, Jaroslaw P. Maciejewski, Zoe Bass, Zehra Tombul, Carlos. I. A. Santos, Munevver N. Duran, Hussein Awada, Ibrahim Ibrahim, Alper Olcal, Yusuf Ozcan, Leslie Guerrero, Julio Alvarenga Thiebaud, Taha Bat
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100163.
https://doi.org/10.1016/j.bneo.2025.100163
Published: 2025
Includes: Supplemental data
Journal Articles

Analyses of transplantation outcomes for adult patients with mixed-phenotype acute leukemia

Open Access
Clinical Trials & Observations
Tomoyasu Jo, Tadakazu Kondo, Shohei Mizuno, Shinichi Kako, Noriko Doki, Naoyuki Uchida, Masatsugu Tanaka, Tetsuya Nishida, Takahiro Fukuda, Masashi Sawa, Yoshinobu Kanda, Satoru Takada, Yuta Hasegawa, Yuta Katayama, Satoshi Yoshihara, Koji Kawamura, Marie Ohbiki, Yoshiko Atsuta, Masamitsu Yanada, Yasuyuki Arai
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100166.
https://doi.org/10.1016/j.bneo.2025.100166
Published: 2025
Includes: Supplemental data
Journal Articles

Ivosidenib or venetoclax combined with hypomethylating agents in IDH1 -mutated acute myeloid leukemia: a real-world study

Open Access
Curtis A. Lachowiez, B. Douglas Smith, Alexander Joseph Ambinder, Gary Binder, Anne Angiolillo, Ravi Potluri, Eros Papademetriou, Thomas W. LeBlanc
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100152.
https://doi.org/10.1016/j.bneo.2025.100152
Published: 2025
Journal Articles

How to drug a leukemic stem cell: deciphering heterogeneity for better specificity

Open Access
Alice Worker, Nicholas Jinks, Peter Woodmancy, Claire Seedhouse, Sophie G. Kellaway
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100146.
https://doi.org/10.1016/j.bneo.2025.100146
Published: 2025
Journal Articles

Posttranscriptional activity of eIF4E contributes to HoxA9-driven leukemogenesis

Open Access
Fang Zhou, Biljana Culjkovic-Kraljacic, Christian Bach, Li Feng, Yuta Mishima, Katherine L. B. Borden, Daniel G. Tenen
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100132.
https://doi.org/10.1016/j.bneo.2025.100132
Published: 2025
Includes: Supplemental data
Journal Articles

Targeting CDK9 inhibits the growth of KMT2A-rearranged infant leukemia and demonstrates synergy with menin inhibition

Open Access
Ritul Sharma, Chunfen Zhang, Ravi Shah, Melanie M. Frigault, Amy J. Johnson, David Spencer Mangum, Luke D. Maese, Norman J. Lacayo, Aru Narendran
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100148.
https://doi.org/10.1016/j.bneo.2025.100148
Published: 2025
Includes: Supplemental data
Journal Articles

Three-year follow-up of low-dose, early-start gilteritinib maintenance in posttransplant patients with R/R FLT3 mut AML

Open Access
Clinical Trials & Observations
Toshiki Terao, Ken-ichi Matsuoka, Takumi Kondo, Yoshinobu Maeda
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100141.
https://doi.org/10.1016/j.bneo.2025.100141
Published: 2025
Journal Articles

SRSF2 mutations in CCUS, MDS and AML: a cross-entity study

Open Access
Sandra Huber, Sarah Ochmann, Stephan Hutter, Veronika Ecker, Manja Meggendorfer, Gregor Hoermann, Torsten Haferlach, Claudia Haferlach, Isolde Summerer
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100144.
https://doi.org/10.1016/j.bneo.2025.100144
Published: 2025
Includes: Supplemental data
Journal Articles

Omacetaxine and venetoclax in relapsed/refractory acute myeloid leukemia or myelodysplastic syndrome with mutant RUNX1

Open Access
Clinical Trials & Observations
Courtney D. DiNardo, Wei-Ying Jen, Guillermo Montalban-Bravo, Xuemei Wang, Sanam Loghavi, Sravanthi Lavu, Nicholas J. Short, Kelly Chien, Ghayas C. Issa, Naveen Pemmaraju, Musa Yilmaz, Michael Andreeff, Gautam Borthakur, Tapan M. Kadia, Naval G. Daver, Guillermo Garcia-Manero, Christopher P. Mill, Xiaoping Su, Warren Fiskus, Kapil N. Bhalla
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100145.
https://doi.org/10.1016/j.bneo.2025.100145
Published: 2025
Journal Articles

Intensive chemotherapy vs venetoclax/hypomethylating agents for patients aged 60 to 75 years with favorable, NPM1-mutated AML

Open Access
Clinical Trials & Observations
Andrew D Zale, Venkata Preetam Sandeep Kaduluri, Jonathan A Webster, Mark J Levis, Ivana Gojo, Amy E DeZern, Gabriel Ghiaur, Lukasz P Gondek, William Brian Dalton, Theodoros Karantanos, Tania Jain, Gabrielle T Prince, Richard J Jones, B. Douglas Smith, Alexander J Ambinder
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100133.
https://doi.org/10.1016/j.bneo.2025.100133
Published: 2025
Includes: Supplemental data
Journal Articles

Targeting scavenger receptor class B type 1 with a bioinspired ligand induces apoptosis or ferroptosis in AML

Open Access
Adam Y. Lin, Jonathan S. Rink, Eva Yang, Sara Small, Jessica J. Gerber, Taylor J. Zak, Jessica Altman, Yasmin Abaza, Leonidas C. Platanias, Leo I. Gordon, C. Shad Thaxton
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100122.
https://doi.org/10.1016/j.bneo.2025.100122
Published: 2025
Includes: Supplemental data
Journal Articles

Do all patients with chronic phase CML require a diagnostic bone marrow biopsy in the modern TKI era?

Open Access
Noel F. T. Fong, David M. Ross, David T. Yeung, Timothy P. Hughes, Naranie Shanmuganathan
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100138.
https://doi.org/10.1016/j.bneo.2025.100138
Published: 2025
Journal Articles

Juvenile myelomonocytic leukemia stem cells are sensitive to NK cell–mediated lysis and express targetable antigens

Open Access
Shannalee Martinez, Vladimir V. Senyukov, Suheyla Hasgur, Arianexys Aquino-López, Peter D. Emanuel, Y. Lucy Liu, Elliot Stieglitz, Gregory Behbehani, Amanda R. Campbell, Dean A. Lee
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (4): 100135.
https://doi.org/10.1016/j.bneo.2025.100135
Published: 2025
Includes: Supplemental data
Journal Articles

Beat AML genetic risk stratification model in a cohort of older VEN/HMA-treated patients with AML

Open Access
Fieke W. Hoff, Ashley O. Yocum, Uma M. Borate, Alice S. Mims, John C. Byrd, Yazan F. Madanat
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (3): 100125.
https://doi.org/10.1016/j.bneo.2025.100125
Published: 2025
Includes: Supplemental data
Journal Articles

PPARγ-induced upregulation of fatty acid metabolism confers resistance to venetoclax and decitabine therapy in AML

Open Access
Kotoko Yamatani, Tatsuro Watanabe, Kaori Saito, Abdullah Khasawneh, Abhishek Maiti, Zhihong Zeng, Kala Hayes, Shinya Kimura, Courtney D. DiNardo, Xiaoping Su, Shuko Nojiri, Yasushi Okazaki, Michael Andreeff, Marina Konopleva, Yoko Tabe
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (3): 100121.
https://doi.org/10.1016/j.bneo.2025.100121
Published: 2025
Includes: Supplemental data
Journal Articles

Replication of a GWAS signal near HLA-DQA2 with AML using a disease-only cohort and external population-based controls

Open Access
Rose Laflamme, Véronique Lisi, Josée Hébert, Guy Sauvageau, Sébastien Lemieux, Vincent-Philippe Lavallée, Guillaume Lettre
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (3): 100118.
https://doi.org/10.1016/j.bneo.2025.100118
Published: 2025
Includes: Supplemental data
Journal Articles

Targeting HASPIN kinase disrupts SR protein–mediated RNA splicing and synergizes with BCL-2 inhibitor venetoclax in AML

Open Access
Mengdan Liu, Ming Yan, Amanda G. Davis, Samuel A. Stoner, Edward D. Ball, Dong-Er Zhang
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (3): 100107.
https://doi.org/10.1016/j.bneo.2025.100107
Published: 2025
Includes: Supplemental data
Journal Articles

Phase 1 trial of venetoclax with cladribine, cytarabine, G-CSF, and mitoxantrone for AML and high-grade myeloid neoplasm

Open Access
Suravi Raychaudhuri, Ted A. Gooley, Allegra Rasmussen, Kim Quach, Eva Gill, Anna B. Halpern, Jacob S. Appelbaum, Cristina M. Ghiuzeli, Paul C. Hendrie, Ryan D. Cassaday, Roland B. Walter, Mary-Elizabeth M. Percival
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (3): 100085.
https://doi.org/10.1016/j.bneo.2025.100085
Published: 2025
Includes: Supplemental data
Journal Articles

Genomic landscape and clonal architecture in pediatric myeloid neoplasms with chromosome 7 deletions

Open Access
Tamara Westover, Michael P. Walsh, Sherif Abdelhamed, Emily Xiong, Jing Ma, Guangchun Song, Melvin E. Thomas, III, Masayuki Umeda, Jamie L. Maciaszek, Jasmine C. Wong, Astrid Wintering, Lu Wang, Peter D. Emanuel, Mignon L. Loh, Sarah K. Tasian, Elliot Stieglitz, Jason R. Schwartz, Kevin M. Shannon, Jeffery M. Klco
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (2): 100093.
https://doi.org/10.1016/j.bneo.2025.100093
Published: 2025
Includes: Supplemental data
Journal Articles

Response and outcomes of patients with IDH1/2- mutated accelerated/blast-phase myeloproliferative neoplasms

Open Access
Leah A. Goldberg, James J. Yoon, Hannah Johnston, Marta B. Davidson, Alexa Siddon, Rory M. Shallis, Evan C. Chen, Madelyn Burkart, Timothy S. Oh, Sunil G. Iyer, Ellen Madarang, Chandrasekar Muthiah, Joshua Kassner, Raajit K. Rampal, Guru Subramanian Guru Murthy, Terrence Bradley, Yasmin Abaza, Jacqueline S. Garcia, Vikas Gupta, Kristen M. Pettit, Olatoyosi Odenike, John F. Cursio, Anand A. Patel
Journal: Blood Neoplasia
Blood Neoplasia (2025) 2 (2): 100089.
https://doi.org/10.1016/j.bneo.2025.100089
Published: 2025
Includes: Supplemental data