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Journal Articles

De Novo Design of a Miniprotein That Functions As an Adapter for CAR-T Cells and Enables Modular Tumor Targeting for the Treatment of AML

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Maria Llases, Craig McKay, Sakeena Syed, Zach Caruolo, Lindsay Webb, Fred Mermelstein, Carl Novina, Nathalia Rodriguez, John Newcomb, Vitalyi Andrusyshyn, Ian Truebridge, Tessa Howard, Bobby Sandage, Edson Carcamo Noriega, Frank Teets, James Bowman, III, Xavier Michelet, Christopher Bahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 7143.
https://doi.org/10.1182/blood-2024-206191
Published: 2024
Journal Articles

Ubiquitin-activating enzyme inhibition induces an unfolded protein response and overcomes drug resistance in myeloma

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Junling Zhuang, Fazal Shirazi, Ram Kumar Singh, Isere Kuiatse, Hua Wang, Hans C. Lee, Zuzana Berkova, Allison Berger, Marc Hyer, Nibedita Chattopadhyay, Sakeena Syed, Judy Qiuju Shi, Jie Yu, Vaishali Shinde, Stephen Tirrell, Richard Julian Jones, Zhiqiang Wang, R. Eric Davis, Robert Z. Orlowski
Journal: Blood
Blood (2019) 133 (14): 1572–1584.
https://doi.org/10.1182/blood-2018-06-859686
Published: 2019
Includes: Supplemental data
Journal Articles

The Anti-Tumor Effect of the Ubiquitin-Activating Enzyme (UAE) Inhibitor TAK-243 on Pre-Clinical Models of Multiple Myeloma

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Junling Zhuang, MD PhD, Hans Lee, MD, Isere Kuiatse, PhD, Hua Wang, PhD, Fazal Shirazi, PhD, Allison Berger, PhD, Marc Hyer, PhD, Nibedita Chattopadhyay, PhD, Sakeena Syed, Judy Qiuju Shi, Jie Yu, M.S., Vaishali Shinde, Anna Kreshock, Stephen Tirrell, PhD, Saurabh Menon, PhD, Richard Julian Jones, PhD, Robert Z. Orlowski, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3296.
https://doi.org/10.1182/blood.V128.22.3296.3296
Published: 2016
Journal Articles

Ninlaro (ixazomib) and Brentuximab Vedotin (ADCETRIS) Combination Results in Synergistic Antitumor Activity in Mouse Models of CD30 Positive Anaplastic Large Cell Lymphoma

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Nibedita Chattopadhyay, PhD, Sakeena Syed, Yuhong Zhang, Jie Yu, M.S., Dan He McDougall, Lunyin Yu Yu, Stephen Tirrell, PhD, Allison Berger, PhD, Helgi van de Velde, MD PhD, Christopher Tremblay, Dirk Huebner, MD
Journal: Blood
Blood (2016) 128 (22): 1842.
https://doi.org/10.1182/blood.V128.22.1842.1842
Published: 2016